CRDAMC Homepage | CRDAMC Library Phone #: (254) 288-8366 | CRDAMC Library Fax #: (254) 288-8368

Search Health Library

Niacin

Image for niacin Niacin, also known as vitamin B3, is a water-soluble vitamin. Water-soluble vitamins are stored in the body in very limited amounts and are excreted through the urine. Therefore, it is a good idea to have them in your daily diet. In addition to getting niacin from dietary sources, the body can synthesize a form of niacin from the amino acid tryptophan.

Functions

Niacin’s functions include:

  • Aiding in the catabolism (breakdown) of carbohydrate, fat, protein, and alcohol to produce energy
  • Supplying energy to all body cells
  • Assisting in fatty acid and cholesterol synthesis
  • Helping the formation of red blood cells
  • Assisting in the metabolism of several drugs and toxins
  • Maintaining the integrity of all body cells

Recommended Intake:    TOP

Age Group (in years)Recommended Dietary Allowance
MalesFemales
1-36 mg6 mg
4-88 mg8 mg
9-1312 mg12 mg
14 and older16 mg14 mg
Pregnancyn/a18 mg
Lactatingn/a17 mg

Niacin Deficiency    TOP

A niacin deficiency is called pellagra. The most common symptoms affect the skin, the digestive system, and the nervous system. Symptoms of niacin deficiency include:

  • Thick, dark, scaly pigmented rash on skin areas exposed to sunlight, heat, or mild trauma
  • Bright red tongue
  • Vomiting
  • Diarrhea
  • Irritability
  • Headache
  • Insomnia
  • Memory loss
  • Depression
  • Fatigue
  • Disorientation

If left untreated, pellagra can lead to death.

Niacin Toxicity    TOP

For adults, the tolerable upper intake level (UL) for niacin from dietary sources and supplements combined is 35 mg. Niacin toxicity does not seem to occur when its only source is foods which have not been fortified with niacin. Symptoms of niacin toxicity have been reported in people using niacin supplements.

Symptoms of toxicity include:

  • Flushing of the skin, primarily on the face, arms, and chest
    *This side effect may occur at doses as low as 30 mg/day
  • Itching
  • Nausea
  • Vomiting
  • Skin rash
  • Dry skin
  • Headache
  • Signs of liver toxicity, including jaundice and elevated liver enzymes

Major Food Sources    TOP

FoodServing Size Niacin Content
(mg)
Breakfast cereal (unfortified)1 cup5-7 (check Nutrition Facts label)
Chicken, roasted without skin3 ounces7.3
Tuna, packed in water3 ounces11.3
Salmon, broiled3 ounces8.5
Turkey, roasted white meat3 ounces10
Avocado5 ounces2.9
Peanuts, dry roasted1 ounce3.8
Beef3 ounces5.8
Pasta, enriched, boiled1 cup2.4
Lentils, cooked1 cup2.1
Lima beans, cooked1 cup1.8
Bread, whole wheat1 slice1.3

Health Implications    TOP

Populations at Risk for Niacin Deficiency

The following populations may be at risk for niacin deficiency or have an increased need for niacin and may require a supplement:

  • People who consume excessive amounts of alcohol
  • People taking the antituberculosis drug isoniazid
  • People with Hartnup's disease

High Cholesterol

Several well-designed clinical studies have shown that niacin can lower LDL-cholesterol and triglycerides (high blood levels of LDL-cholesterol and triglycerides are considered unhealthy); studies have also shown that niacin can raise HDL-cholesterol (higher blood levels of HDL-cholesterol are considered healthy). However, the studies that found positive results used pharmacologic doses of niacin. These doses are much larger than the current recommended dietary allowances (RDA) and should only be used under the supervision of a qualified healthcare provider.

Tips For Increasing Your Niacin Intake:    TOP

To help increase your intake of niacin:

  • Use mashed avocado in place of cream cheese, butter, or margarine on your morning bagel, or mayonnaise on your lunchtime sandwich.
  • For lunch, have a few slices of lean turkey with lettuce and tomato on wheat bread.
  • Grill salmon, halibut, or trout for dinner. Crack a bit of pepper, sprinkle some salt, squeeze a touch of lemon, and finish off with a splash of olive oil.
  • Munch on a handful of peanuts as an afternoon snack.
  • Bake a potato and top with black beans, salsa, and cheese or steamed broccoli, carrots, and a spoonful or 2 of low-fat sour cream.
  • If you take a vitamin supplement, make sure it contains niacin (but no more than 100% of the RDA).

RESOURCES:

American Society for Nutrition
http://www.nutrition.org
Eat Right—American Academy of Nutrition and Dietetics
http://www.eatright.org

CANADIAN RESOURCES:

Dietitians of Canada
http://www.dietitians.ca

References:

Avocado Nutrition Facts and Label. Avocado Central website. Available at:
...(Click grey area to select URL)
Accessed May 5, 2016.
Niacin. Oregon State University Linus Pauling Institute's Micronutrient Information Center website. Available at:
...(Click grey area to select URL)
Accessed May 5, 2016.
Last reviewed May 2016 by Michael Woods, MD
Last Updated: 6/5/2014

EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.

To send comments or feedback to our Editorial Team regarding the content please email us at healthlibrarysupport@ebsco.com. Our Health Library Support team will respond to your email request within 2 business days.

Health Library: Editorial Policy | Privacy Policy | Terms and Conditions | Support
36000 Darnall Loop Fort Hood, Texas 76544-4752 | Phone: (254) 288-8000