Symptoms of sickle cell disease may be noticed as soon as 4 months of age, or it may go undetected until later in the baby’s first year of life.
Oxygen deprivation is a result of blood vessels that are blocked by the misshapen red blood cells of sickle cell anemia. Periods of acute oxygen deprivation cause severely painful episodes called pain crises. The location of the pain and the types of symptoms depend on what tissues or organs of the body have been deprived of oxygen.
Symptoms of sickle cell disease include:
Other medical conditions that can result from sickle cell disease include:
Sickle cell crisis can be provoked by certain triggers, including:
Sickle cell disease. Kids Health—Nemours Foundation website. Available at: http://kidshealth.org/en/parents/sickle-cell-anemia.html. Updated September 2012. Accessed July 1, 2013.
Sickle cell disease in adults and adolescents. EBSCO DynaMed Plus website. Available at:http://www.dynamed.com/topics/dmp~AN~T902929/Sickle-cell-disease-in-adults-and-adolescents. Updated October 4, 2016. Accessed October 5, 2016.
Sickle cell disease in infants and children. EBSCO DynaMed Plus website. Available at:http://www.dynamed.com/topics/dmp~AN~T902928/Sickle-cell-disease-in-infants-and-children. Updated September 20, 2016. Accessed October 5, 2016.
What are the signs and symptoms of sickle cell disease? National Heart, Lung, and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/sca/signs. Updated August 2, 2016. Accessed December 13, 2016.
Last reviewed December 2016 by Marcin Chwistek, MD Last Updated: 5/20/2015