Rhodiola rosea is a plant that grows in the mountains of Europe and Asia. The root has been used to ease feelings of stress, anxiety, and fatigue. Rhodiola rosea can be taken as a pill, powder, or extract.
200 milligrams twice daily
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It is likely safe to take rhodiola rosea in small doses for a short time, but it may cause lightheadedness, dry mouth, or excessive salivation.C2 Not enough studies have been done to say whether it is safe to use for a long period. It is also not known whether it is safe to take by women who are pregnant or breastfeeding.
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A1. Cropley M, Banks AP, et al. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Phytother Res. 2015 Dec;29(12):1934-1939.
B1. Darbinyan V, Aslanyan G, et al. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Nord J Psychiatry. 2007;61(5):343-348.
B2. Dwyer AV, Whitten DL, et al. Herbal medicines, other than St. John's Wort, in the treatment of depression: a systematic review. Altern Med Rev. 2011 Mar;16(1):40-49.
B3. Ross SM. Rhodiola rosea (SHR-5), Part 2: A standardized extract of Rhodiola rosea is shown to be effective in the treatment of mild to moderate depression. Holist Nurs Pract. 2014;28(3):217-221.
B4. Mao JJ, Xie SX, et al. Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. Phytomedicine. 2015 Mar 15;22(3):394-399.
C. Mental Fatigue
C1. Olsson EM, von Schéele B, et al. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009 Feb;75(2):105-112.
C2. Ishaque S, Shamseer L, et al. Rhodiola rosea for physical and mental fatigue: a systematic review. BMC Complement Altern Med. 2012 May 29;12:70.
Last reviewed July 2019 by EBSCO NAT Review Board Eric Hurwitz, DC Last Updated: 3/30/2020