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Uric acid comes from the break down of purine from food or human cells. Sometimes the body makes too much uric acid. It may also have problems passing uric acid out of the body through the kidneys. Uric acid crystals form when uric acid levels get too high. This leads to gout.
Risk Factors TOP
Gout is more common in men and older adults. But it can happen in men and women at any age.
Other risk factors are:
Certain foods and drinks may also raise your chances of gout.
Here are some symptoms:
Most people with gout have more than one attack. This attack may be on many joints. Chalky deposits of uric acid called tophi can form. They often form in the elbows and earlobes, but may form in any part of the body.
You will be asked about your symptoms and health history. A physical exam will be done. Fluid from the affected joint will be taken. This fluid will be tested for uric acid crystals.
Your blood and urine may be tested.
Pictures may be taken of your body. This can be done with:
Treatment depends on whether the gout is acute or recurrent.
In general, the sooner you get medical help for an acute attack, the better. Treatment depends on:
Putting an ice pack on the joint may ease the pain. Keeping the weight of clothes or bed covers off the joint can also help.
Medications may include:
If you get gout more than once, you may be advised to treat it with:
If you have recurrent gout, or you have kidney stones, tophi, or reduced kidney function, you may be given medicine to:
To lower your chance of getting gout:
American Arthritis Society
Gout. American College of Rheumatology website. Available at:
Gout. Arthritis Foundation website. Available at:
Gout. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115215/Gout . Updated March 22, 2018. Accessed June 5, 2018.
Gout. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at:
Gout overview. Family Doctor—American Academy of Family Physicians website. Available at:
Gout management - prevention of recurrent attacks. EBSCO DynaMedPlus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115215/Gout . Updated April 24, 2018. Accessed June 5, 2018.
1/4/2011 DynaMed Plus Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T115215/Gout : Man CY, Cheung IT, Cameron PA, Rainer TH. Comparison of oral prednisolone/paracetamol and oral indomethacin/paracetamol combination therapy in the treatment of acute gout-like arthritis: a double-blind, randomized, controlled trial. Ann Emerg Med. 2007;49:670-677. Epub 2007 Feb 5.
1/4/2011 DynaMed Plus Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T115215/Gout : Choi HK, Willett W, Curhan G. Fructose-rich beverages and risk of gout in women. JAMA. 2010;304(20):2270-2278.
4/24/2014 DynaMed Plus Systematic Literature Surveillance
http://www.dynamed.com/topics/dmp~AN~T115215/Gout: Wise JN, Weissman BN, et al. American College of Radiology (ACR) Appropriateness Criteria for chronic foot pain. Available at:
Last reviewed May 2018 by
EBSCO Medical Review Board
Warren A. Bodine, DO, CAQSM
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