You will be asked about your symptoms and health history. A physical exam will be done. There are no specific tests to diagnose PD. The doctor will ask many questions. This will help to rule out other causes of your symptoms.
Tests to rule out other conditions may also include:
Imaging tests may be needed to view the brain and spine. This can be done with:
There are no known treatments to cure PD. There are also no proven treatments to slow or stop its progression. Some medications may help to improve symptoms. Over time, the side effects of the medication may become troublesome. The medications may also lose their effectiveness.
Medicines that may be used to treat PD include:
Monoamine oxidase inhibitors
Depression or hallucinations may also occur with PD. They can also be caused by treatment. These conditions may be managed with medicine such as:
Selective serotonin reuptake inhibitors (SSRIs)
Other medication may help to manage other health risks such as:
Cognitive training works on areas of the brain that control certain functions. It may help improve the ability to do daily tasks. Activities are meant to promote and increase brain fitness through learning or exercises. It works best in conjunction with other healthy lifestyle habits. This training may lead to improvements in reasoning, problem solving, and working memory.
Alvarez MV, Evidente VG. Understanding drug induced parkinsonism: Separating pearls from oysters. Neurology. 2008;70(8):e32-e34.
Burbulla LF, Song P, Mazulli JR. Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinsons disease. Science. 2017;357(6357):1255-61.
Li F, Harmer P, Fitzgerald K, et al. Tai chi and postural instability in patients with Parkinson’s disease. N Engl J Med. 2012;366(6):511-519.
Liu R, Gao X, Lu Y, Chen H. Meta-analysis of the relationship between Parkinson disease and melanoma. Neurology. 2011;76(23):2002-2009.
Managing your PD. Parkinson’s Disease Foundation website. Available at: ...(Click grey area to select URL) Accessed October 2, 2017.
Nielsen NM, Rostgaard K, Hjalgrim H, Aaby P, Askgaard D. Poliomyelitis and Parkinson disease. JAMA. 2002;287(13):1650-1651.
NINDS Parkinson's disease information page.
National Institute of Neurological Disorders and Stroke
website. Available at:
https://www.ninds.nih.gov/Disorders/All-Disorders/Parkinsons-Disease-Information-Page. Accessed October 2, 2017.
Obeso JA, Rodriguez-Oroz MC, Goetz CG, et al. Missing pieces in the Parkinson’s disease puzzle.
Nat Med. 2010;16(6):653-661.
Parkinson's disease. American Association of Neurological Surgeons website. Available at: ...(Click grey area to select URL) Accessed October 2, 2017.
Perlmutter JS, Eidelberg D. To scan or not to scan: DaT is the question. Neurology. 2012;78(10):688-689.
Ristić AJ, Vojvodić N, Janković S, Sindelić A, Sokić D. The frequency of reversible parkinsonism and cognitive decline associated with valproate treatment: a study of 364 patients with different types of epilepsy.
Samii A, Nutt JG, Ransom BR. Parkinson's disease.
Schenkman N, Hall DA, Barón AE, Schwartz RS, Mettler P, Kohrt WM. Exercise for people in early- or mid-stage Parkinson disease: A 16-month randomized controlled trial. Phys Ther. 2012;92(11):1395-1410.
Siderowf A, Stern M. Update on Parkinson's disease.
Ann Intern Med. 2003;138(8):651-658.
Wider C, Wszolek CK. Movement disorders: Insights into mechanisms and hopes for treatments.
Lancet Neurology. 2009;8(1):8-10.
4/7/2014 DynaMed Plus Systematic Literature Surveillance
Marras C, Hincapié CA, Kristman VL, et al. Systematic review of the risk of Parkinson's disease after mild traumatic brain injury: results of the international collaboration on mild traumatic brain injury prognosis. Arch Phys Med Rehabil. 2014;95(3S):S238-S244.
9/3/2014 DynaMed Plus Systematic Literature Surveillance. Available at:
http://www.dynamed.com/topics/dmp~AN~T115172/Parkinson-disease: Wippold FJ, Brown DC, Broderick DF, et al. American College of Radiology (ACR) Appropriateness Criteria for dementia and movement disorders. Available at: ...(Click grey area to select URL) Updated 2014. Accessed August 28, 2015.
10/17/2016 DynaMed Plus Systematic Literature Surveillance
: Ni M Signorile JF, et al. Comparative effect of power training and high-speed yoga on motor function in older patients with Parkinson disease. Arch Phys Med Rehabil. 2016 Mar;97(3):345-354.
Last reviewed September 2018 by
EBSCO Medical Review Board
Rimas Lukas, MD Last Updated:7/13/2018