Your doctor will use one of the following methods to do the biopsy:
Transrectal biopsy (most common method)—Your doctor will insert a small ultrasound device into the rectum. This device will produce sound waves to create an image of the prostate. These images will help guide placement of the needle. Your doctor will then insert the needle through the wall of the rectum and into the prostate gland.
Transurethral biopsy—Your doctor will insert a lighted flexible tube through the tip of the penis and into the urethra. The urethra carries urine from the bladder. Your doctor will get the biopsy with a cutting loop that is passed through the flexible tube.
Perineal biopsy—Your doctor will make a small incision in the perineum. The perineum is the area between the scrotum and the rectum. The doctor will insert a small needle into the prostate gland to get the biopsy.
Blood in the urine, stool, or semen is normal. This may last several days. You may be advised to avoid strenuous activity a day or two after the procedure. Follow your doctor's instructions on caring for the biopsy site.
After the sample is taken, it will be sent to a pathologist for examination under a microscope. If cancer is present, your doctor will work with you to develop a treatment plan.
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