If both the doctors and the participants of a scientific study know who is receiving a treatment under study and who is receiving another treatment (or no treatment at all), the procedure is called an open trial (or open study). The results have to be taken with a handful of salt: open trials are not at all reliable. In such studies, it isn't possible to determine which effects are due to the treatment itself and which are due to the placebo effect. The main use of open trials is to look for severe adverse effects of a treatment. For this reason, they are sometimes called "drug-monitoring studies."
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at firstname.lastname@example.org. Our Health Library Support team will respond to your email request within 2 business days.
All rights reserved.