Risk Factors for End-stage Renal Disease (ESRD)

by Michael Jubinville, MPH

A risk factor is something that raises your chances of getting a health problem.

You can progress to ESRD with or without the factors listed below. The more you have, the greater your chances of getting it. Ask your doctor what you can do to lower your risk.

The risk of ESRD gets higher as you age. It is also higher in men.

Other factors that increase the chances of ESRD:

Certain health problems such as diabetes or high blood pressure
Kidney problems such as acute kidney injury, nephrotic syndrome, glomerulonephritis, or kidney stones
Black race
Obesity as a teenager
Certain medicines such as proton pump inhibitors for gastroesophageal reflux disease
Systemic lupus erythematosus
Problems with certain genes
Some habits such as smoking or drug use

References:

Chronic kidney disease (CKD) in adults. EBSCO DynaMed website. Available at: https://www.dyname.... Updated January 18, 2019. Accessed July 18, 2019.

Kidney failure (ESRD) causes, symptoms, & treatments. American Kidney Fund website. Available at:
...(Click grey area to select URL)
Accessed July 18, 2019.

Murphree DD, Thelen SM. Chronic kidney disease in primary care. J Am Board Fam Med. 2010;23(4):542-550.

What is kidney failure? National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: https://www.niddk.nih.gov/health-information/kidney-disease/kidney-failure/what-is-kidney-failure. Updated January 2018. Accessed July 18, 2019.

What is kidney failure? National Kidney Foundation website. Available at: https://www.kidney.org/atoz/content/KidneyFailure. Accessed July 18, 2019.

Last reviewed July 2019 by EBSCO Medical Review Board Adrienne Carmack, MD
Last Updated: 10/4/2019

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