Primary ovarian insufficiency (POI) is the loss of ovarian function before 40 years of age. The ovaries are two small, oval-shaped organs in the pelvis. They release eggs and certain hormones called estrogen and progesterone.
Committee opinion no. 605: primary ovarian insufficiency in adolescents and young women. Obstet Gynecol. 2014;124(1):193-197. Reaffirmed 2020. Available at: https://www.acog.org/Clinical-Guidance-and-Publications/Committee-Opinions/Committee-on-Adolescent-Health-Care/Primary-Ovarian-Insufficiency-in-Adolescents-and-Young-Women. Accessed February 24, 2021.
Premature ovarian failure: early menopause. American Pregnancy Association website. Available at: http://americanpregnancy.org/womens-health/premature-ovarian-failure. Accessed February 24, 2021.
Primary ovarian insufficiency (POI). EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/primary-ovarian-insufficiency-poi. Accessed February 24, 2021.
Primary ovarian insufficiency (POI). National Institute of Child Health and Human Development website. Available at: https://www.nichd.nih.gov/health/topics/poi. Accessed February 24, 2021.
Torrealday S, Kodaman P, et al. Premature Ovarian Insufficiency - an update on recent advances in understanding and management. F1000Res. 2017;6:2069.
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