Some may also have an allergic reaction to sulfites. This means sulfites cause an autoimmune reaction, which may cause:
Your doctor will ask about your symptoms and medical history. A physical exam will be done. The doctor may ask specific questions about what you were doing when the symptoms occurred. The exact cause may not be clear in the first visit. Your doctor may ask you to keep a diary of your symptoms to help determine the cause.
Your bodily fluids and tissues may be tested to eliminate other causes. This can be done with:
Allergy testing. American College of Allergy, Asthma & Immunology website. Available at: http://acaai.org/allergies/treatment/allergy-testing. Accessed December 15, 2017.
Boyce JA, Assa'ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. Nutr Res. 2011;31(1):61-75.
Food allergy. National Institute of Allergy and Infectious Diseases website. Available at: https://www.niaid.nih.gov/diseases-conditions/food-allergy. Updated March 27, 2017. Accessed December 15, 2017.
Garcia-Gavin J, Parente J, Goossens A. Allergic contact dermatitis caused by sodium metabisulfite: a challenging allergen: a case series and literature review. Contact Dermatitis. 2012;67(5):260-269.
Grotheer P, Marshall M, Simonne A. Sulfites: separating fact from fiction. University of Florida website. Available at: http://edis.ifas.ufl.edu/fy731. Accessed December 15, 2017.
Papaioannou R, Pfeiffer C. Sulfite sensitivity—unrecognized threat: is molybdenum deficiency the cause? Orthomolecular website. Available at: http://orthomolecular.org/library/jom/1984/pdf/1984-v13n02-p105.pdf. Accessed December 15, 2017.
Sulfite allergy. Australasian Society of Clinical Immunology and Allergy website. Available at: https://www.allergy.org.au/patients/product-allergy/sulfite-allergy. Updated 2014. Accessed December 15, 2017.
Sulfite sensitivity. Cleveland Clinic website. Available at: https://my.clevelandclinic.org/health/articles/11323-sulfite-sensitivity. Updated December 30, 2016. Accessed December 15, 2017.
Sulfites: FDA guide to foods and drugs with sulfites. The Extension Toxicology Network website. Available at: http://extoxnet.orst.edu/faqs/additive/sulf_tbl.htm. Accessed December 15, 2017.
Last reviewed November 2018 by
EBSCO Medical Review Board
Marcie L. Sidman, MD
Last Updated: 12/20/2014
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