Corzide® (as a combination product containing Bendroflumethiazide, Nadolol)
Do not stop taking nadolol without talking to your doctor. Suddenly stopping nadolol may cause chest pain or heart attack. Your doctor will probably decrease your dose gradually.
WHY is this medicine prescribed?
Nadolol is used alone or in combination with other medications to treat high blood pressure. It is also used to prevent angina (chest pain). Nadolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
HOW should this medicine be used?
Nadolol comes as a tablet to take by mouth. It is usually taken once a day with or without food. To help you remember to take nadolol, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nadolol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor may start you on a low dose of nadolol and gradually increase your dose.
Nadolol controls high blood pressure and angina but does not cure them. It may take a few weeks before you feel the full benefit of nadolol. Continue to take nadolol even if you feel well.
Are there OTHER USES for this medicine?
Nadolol is also used sometimes to prevent migraine headaches, to treat irregular heartbeat, and to treat tremors caused by Parkinson's disease. Talk to your doctor about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What SPECIAL PRECAUTIONS should I follow?
Before taking nadolol,
tell your doctor and pharmacist if you are allergic to nadolol, any other medications, or any ingredients in nadolol tablets. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: insulin and oral medications for diabetes; and reserpine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have or have ever had asthma or other lung diseases, a slow heart rate, heart or kidney disease, diabetes, severe allergies, or hyperthyroidism (an overactive thyroid gland).
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking nadolol, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking nadolol.
remember that alcohol can add to the drowsiness caused by this medication.
you should know that if you have allergic reactions to different substances, your reactions may be worse while you are using nadolol, and your allergic reactions may not respond to the usual doses of injectable epinephrine.
What SPECIAL DIETARY instructions should I follow?
If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.
What should I do IF I FORGET to take a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What SIDE EFFECTS can this medicine cause?
Nadolol may cause side effects. Tell your doctor if either of these symptoms is severe or does not go away:
dizziness or lightheadedness
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
shortness of breath
swelling of the hands, feet, ankles, or lower legs
unusual weight gain
Nadolol may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( Web Site) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. Web Site
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at Web Site. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
difficulty breathing or swallowing
swelling of the hands, feet, ankles, or lower legs
What OTHER INFORMATION should I know?
Keep all appointments with your doctor. Your blood pressure should be checked regularly to determine your response to nadolol. Your doctor may ask you to check your pulse (heart rate). Ask your pharmacist or doctor to teach you how to take your pulse. If your pulse is faster or slower than it should be, call your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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