Bacteria normally exists in the intestines. It plays an important role in digestion and overall health. Small intestine bacterial overgrowth (SIBO) is when there is too much bacteria in the small intestine.
SIBO is often caused by a problem with the small intestine. Damage or defects to the intestine may slow the flow of food through the area. The slowed food may encourage the increased growth of bacteria. Problems of the intestine may be caused by:
Any condition that affects how food moves through the intestines may increase the risk of SIBO. Examples include:
Bacterial overgrowth syndrome. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/gastrointestinal-disorders/malabsorption-syndromes/bacterial-overgrowth-syndrome. Updated May 2016. Accessed October 3, 2017.
Bures J, Cyrany J, Kohoutova D, et al. Small intestinal bacterial overgrowth syndrome. World J Gastroenterol. 2010;16(24):2978–2990.
Lactose and glucose hydrogen breath test. Cleveland Clinic website. Available at: https://my.clevelandclinic.org/health/articles/lactose-and-glucose-hydrogen-breath-test. Accessed October 3, 2017.
Lin H. Small intestinal bacterial overgrowth. JAMA. 2004;292(7):852-858.
Vanderhoof J, Young R, Murray N, Kaufman SS. Treatment strategies for small bowel bacterial overgrowth in short bowel syndrome. J Pediatr Gastroenterol Nutr. 1998;27(2):155-160.
Last reviewed September 2018 by
EBSCO Medical Review Board
Daus Mahnke, MD
Last Updated: 2/6/2018
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