The parent will not always pass the faulty gene to their child. However, if one parent has the gene defect, it raises the child's risk of FH. If both parents have the gene defect, the child's risk of FH is even higher.
FH itself does not cause symptoms. However, high levels of LDL can lead to:
Familial hypercholesterolemia. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/familial-hypercholesterolemia. Accessed January 20, 2021.
Familial hypercholesterolemia. National Organization of Rare Disorders website. Available at: https://rarediseases.org/rare-diseases/familial-hypercholesterolemia. Accessed January 20, 2021.
Familial hypercholesterolemia. Genetics Home Reference——US National Library of Medicine website. Available at: https://medlineplus.gov/genetics/condition/familial-hypercholesterolemia. Accessed January 20, 2021.
Soran H, Adam S. Hypercholesterolaemia – practical information for non-specialists. Arch Med Sci. 2018 Jan; 14(1): 1–21.
Last reviewed February 2020 by
EBSCO Medical Review Board
Marcin Chwistek, MD
Last Updated: 1/19/2021
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