Peripheral artery disease (PAD) is a condition that leads to a decrease of blood flow to the arms and legs.
PAD is most often caused by a narrowing of blood vessels that supply blood to the arms and legs. The narrowing is usually caused by a buildup of plaque called
atherosclerosis. The build up occurs over long periods of time and is increased with:
Other conditions that can slow blood flow include blood clots and inflammation of the blood vessels. Certain conditions like congenital heart disease can also decrease the amount of oxygen rich blood that reaches the arms and legs.
Prevention and treatment of PAD. American Heart Association website. Available at: http://www.heart.org/HEARTORG/Conditions/VascularHealth/PeripheralArteryDisease/Prevention-and-Treatment-of-PAD_UCM_301308_Article.jsp#.WphMNWrwZQI. Updated February 20, 2018. Accessed March 1, 2018.
11/18/2011 DynaMed's Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T114200/Peripheral-arterial-disease-PAD-of-lower-extremities: Rooke TW, Hirsch AT, Misra S, et al. 2011 ACCF/AHA focused update of the guideline for the management of patients with peripheral artery disease (updating the 2005 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;124(18):2020-2045.
6/29/2018 DynaMed Plus Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Beckman JA, Duncan MS, Alcorn CW, et al. Association of HIV infection and risk of peripheral artery disease. Circulation. 2018 Mar 13 [Epub ahead of print].
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