Cancer is when cells in the body split without control or order. These cells go on to form a growth or tumor. The term cancer refers to harmful growths. These growths attack nearby tissues. They also spread to other parts of the body. It’s not clear exactly what causes these problems. It’s likely a mix of genes and the environment.
Risk factors are not clear since the cause is unknown. This type of cancer is more common in male teenagers who are White. But it can happen at any age.
Symptoms will depend on where the tumor is. General symptoms may include:
May come and go or be constant
Range from mild to severe
May include feeling of pins and needles
Redness and swelling around the area
Weight loss and reduced appetite
Broken bone with no known cause
The doctor will ask about your symptoms and health history. A physical exam will also be done. There are a number of bone issues that cause the same symptoms. Tests will help to confirm Ewing sarcoma.
The doctor will do a biopsy. A sample of tissue will be removed from the area. A lab will look for cancer cells.
Chemotherapy drugs are used to kill tumor cells. Your doctor will prescribe a combination of drugs to be given over a set time. This usually means every 2-4 weeks for several months.
This is often the first step in treatment. It may help to shrink the tumor before other treatment. It can also attack tumors that may have spread to other areas of the body.
The tumor may be removed with surgery. It is often done after chemotherapy to try to shrink the tumor first.
The bone may need repair after the tumor is removed. A
or prosthesis may be needed to support the remaining bone. It may take a number of surgeries to get full use of the limb.
Radiation therapy uses high-energy x-rays to kill tumor cells. It can help shrink tumors before a surgery. It may also be used instead of surgery. It is often given over several weeks.
A high-dose chemotherapy is being tested for ewing sarcoma. This high dose kills off bone marrow. A
stem cell transplant
is then needed to help grow healthy bone marrow. This combination therapy is typically used in cases where the tumor is resistant.
There is no way to prevent Ewing sarcoma since the cause is unknown.
Ewing family of tumors. American Cancer Society website. Available at: https://www.cancer.org/cancer/ewing-tumor.html. Accessed January 29, 2021.
Ewing sarcoma treatment (PDQ)—patient version. National Cancer Institute website. Available at: https://www.cancer.gov/types/bone/patient/ewing-treatment-pdq. Accessed January 29, 2021.
Ewing’s sarcoma. Ortho Info—American Academy of Orthopaedic Surgeons website. Available at: https://orthoinfo.aaos.org/en/diseases--conditions/ewings-sarcoma. Accessed January 29, 2021.
Miser ES, Goldsby RE, Chen Z, et al. Treatment of metastatic Ewing’s sarcoma/primitive neuroectodermal tumor of bone: evaluation of increasing the dose intensity of chemotherapy-a report from the children’s oncology group. Pediatr Blood Cancer. 2007;49(7):894-900.
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