A. Chronic venous insufficiency
A1. Petruzzellis V, Troccoli T, et al. Oxerutins (Venoruton): efficacy in chronic venous insufficiency—a double-blind, randomized, controlled study. Angiology. 2002;53(3):257-263.
A2. Cesarone MR, Belcaro G, et al. Venoruton vs Daflon: evaluation of effects on quality of life in chronic venous insufficiency. Angiology. 2006;57(2):131-138.
A3. Akbulut B. Calcium dobesilate and oxerutin: effectiveness of combination therapy. Phlebology. 2010 Apr;25(2):66-71.
A4. Aziz Z, Tang WL, et al. A systematic review of the efficacy and tolerability of hydroxyethylrutosides for improvement of the signs and symptoms of chronic venous insufficiency. J Clin Pharm Ther. 2015 Apr;40(2):177-185.
A5. Martinez-Zapata MJ, Vernooij RW, et al. Phlebotonics for venous insufficiency. Cochrane Database Syst Rev. 2016 Apr 6;4:CD003229.
B1. Badger C, Preston N, et al. Benzo-pyrones for reducing and controlling lymphoedema of the limbs. Cochrane Database Syst Rev. 2004;(2):CD003140.
C. Post-Thrombotic Syndrome
C1. Morling JR, Broderick C, et al. Rutosides for treatment of post-thrombotic syndrome. Cochrane Database Syst Rev. 2018 Nov 8;11:CD005625.
D. Pregnancy Support
D1. Smyth RM, Aflaifel N, et al. Interventions for varicose veins and leg oedema in pregnancy. Cochrane Database Syst Rev. 2015 Oct 19;(10):CD001066.
E. Venous Leg Ulcers
E1. Scallon C, Bell-Syer SE, et al. Flavonoids for treating venous leg ulcers. Cochrane Database Syst Rev. 2013 May 31;(5):CD006477.