Arsenic toxicity is exposure to toxic amounts of arsenic. Arsenic is a naturally occurring element in the earth’s crust. It has no smell or taste. If you suspect you have been exposed to arsenic, contact your doctor right away.
There are 2 primary forms of arsenic:
Inorganic arsenic—Arsenic combined with hydrogen, oxygen, chlorine, or sulfur. Found in the environment, sometimes as a gas.
Organic arsenic—Arsenic combined with carbon and hydrogen. Found in animals and plants.
Inorganic arsenic is much more harmful than organic arsenic.
Arsenic occurs naturally in soil and minerals, and may enter the air, water, and soil. It is also used:
To preserve or pressure-treat wood—this use is being phased out except for specific applications such as railroad ties and utility poles, but old stocks may still be around and pose a risk
As an ingredient in pesticides
To produce glass
In copper and other metal manufacturing
In the electronics industry
Arsenic toxicity may occur when a person is exposed to toxic amounts of arsenic by:
Breathing air containing arsenic
Eating food contaminated with arsenic
Drinking water contaminated with arsenic
Living in areas with high natural levels of arsenic
Central nervous system (the brain and spinal cord) slows down
Death, which can occur in hours
Symptoms of chronic arsenic exposure include:
Thickening of skin
Discoloration of skin
Small corns or warts on the palms, soles, and torso
Abnormal heart rhythm
Numbness in hands and feet
In addition, people exposed to arsenic may be at a greater risk of developing heart disease.
You will be asked about your symptoms and medical history. A physical exam will be done. It can be difficult to make a diagnosis of arsenic poisoning because symptoms are so varied. If you have concerns about arsenic causing symptoms in yourself or a family member, talk to your doctor.
Your bodily fluids and tissues may be tested. This can be done with:
Hair or fingernail analysis
There is no effective treatment for arsenic toxicity. There is increasing evidence that chelation therapy may benefit some people who were poisoned with arsenic. Chelation therapy involves putting a chemical called a
chelating agent into the bloodstream. The chelating agent combines with a toxin to help remove it from the body. Chelating agents may be given by pill or by injection.
If chelation is not indicated or is ineffective, your treatment will be designed to help manage and control your symptoms. Treatment may include IV hydration, for example.
To help reduce your chances of getting arsenic toxicity:
If you work with arsenic-treated wood at home, wear a dust mask, gloves, and protective clothing. Do not burn any wood that has been treated with arsenic compounds.
If you live in an area with high natural levels of arsenic, use cleaner sources of water and limit contact with soil. If you have well water, have it tested for a variety of contaminants, including arsenic.
Arsenic. Agency for Toxic Substances and Disease Registry website. Available at: http://www.atsdr.cdc.gov/substances/toxsubstance.asp?toxid=3. Updated March 3, 2011. Accessed March 16, 2018.
Arsenic and drinking water from private wells. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/healthywater/drinking/private/wells/disease/arsenic.html. Updated July 1, 2015. Accessed March 16, 2018.
Arsenic—ToxFAQs. Agency for Toxic Substances and Disease Registry website. Available at: http://www.atsdr.cdc.gov/toxfaqs/tfacts2.pdf. Updated August 2007. Accessed March 16, 2018.
Fourth national report on exposure to environmental chemicals. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/exposurereport/pdf/FourthReport.pdf. Accessed March 16, 2018.
Last reviewed March 2018 by
EBSCO Medical Review Board
James Cornell, MD
Last Updated: 2/16/2015
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