Gallbladder cancer is when cancer cells grow in the gallbladder. This is a somewhat rare form of cancer. The gallbladder is a small organ that sits beneath the liver. It stores a digestive fluid called bile.
Cancer happens when cells divide without control or order. These cells grow together to form a tumor. They can invade and damage nearby tissues. They can also spread to other parts of the body.
It is not clear what causes changes in the cells. It is likely a combination of genes and environment.
Gallbladder cancer is more common in older adults and women. It is also more common in people from South America, parts of Asia, and Eastern Europe. Other things that may raise the risk are:
Gallbladder cancer often has no symptoms in the early stages. When symptoms appear, they may be:
Pain in the belly
Pain in the upper back
Nausea and vomiting
Lack of hunger
Feeling weak and tired
Yellowing of the skin and whites of the eyes—
The doctor will ask about your symptoms and health history. A physical exam will be done. Gallbladder cancer is often hard to diagnose because there are no early symptoms. It is often found during abdominal surgery for other reasons.
Cholangiocarcinoma and gallbladder cancer. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/cholangiocarcinoma-and-gallbladder-cancer . Accessed March 25, 2021.
Gallbladder cancer. American Cancer Society website. Available at: https://www.cancer.org/cancer/gallbladder-cancer.html. Accessed March 25, 2021.
Hickman L, Contreras C. Gallbladder cancer: diagnosis, surgical management, and adjuvant therapies. Surg Clin North Am. 2019;99(2):337-355.
Tumors of the gallbladder and bile ducts. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/gallbladder-and-bile-duct-disorders/tumors-of-the-gallbladder-and-bile-ducts. Accessed March 25, 2021.
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at firstname.lastname@example.org. Our Health Library Support team will respond to your email request within 2 business days.