Amyloidosis is a buildup of abnormal proteins called amyloids. The body cannot break down these proteins. Instead, they build up on tissues and organs like the heart, liver, and kidneys. This makes it hard for them to work as they should. This can be deadly. Early treatment can improve outcomes.
There are several types of amyloidosis based on the protein that is involved. This fact sheet focuses on amyloidosis (AL) light chain. It is an abnormal form of antibody proteins.
This problem happens when cells in the bone marrow make abnormal antibodies. These antibodies misfold, bind together, and build up on tissues and organs.
This health problem is most common in people who are 50 to 70 years of age.
Exposure to agent orange or certain weed killers may raise the risk of this health problem.
These health problems may also be linked to AL amyloidosis:
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at email@example.com. Our Health Library Support team will respond to your email request within 2 business days.