A risk factor is something that increases your likelihood of getting a disease or condition.
It is possible to develop rheumatoid arthritis (RA) with or without the risk factors listed below. However, the more risk factors you have, the greater your likelihood of developing RA. If you have a number of risk factors, ask your doctor what you can do to reduce your risk.
RA can develop at any age, but it usually appears between 30 and 50 years of age. RA is more common in women, and it appears later in life for men.
Other factors that may increase your chance of RA include:
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Rheumatoid arthritis. Arthritis Foundation website. Available at: http://www.arthritis.org/about-arthritis/types/rheumatoid-arthritis. Accessed November 29, 2016.
Rheumatoid arthritis. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/joint-disorders/rheumatoid-arthritis-ra. Updated August 2015. Accessed November 29, 2016.
Rheumatoid arthritis. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: http://www.niams.nih.gov/Health_Info/Rheumatic_Disease/default.asp. Updated February 2016. Accessed November 29, 2016.
Rheumatoid arthritis (RA). EBSCO DynaMed website. Available at:http://www.dynamed.com/topics/dmp~AN~T115261/Rheumatoid-arthritis-RA. Updated September 30, 2016. Accessed November 29, 2016.
Sugiyama D, Nishimura K, et al. Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies. Ann Rheum Dis. 2010;69(1):70-81.
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Last reviewed November 2016 by Michael Woods, MD Last Updated: 10/16/2019