Daptomycin injection is used alone or in combination with other medications in adults and children 1 year of age and older to treat certain blood infections or serious skin infections caused by bacteria. Daptomycin injection is in a class of medications called cyclic lipopeptide antibiotics. It works by killing bacteria.
Antibiotics such as daptomycin injection will not work for treating colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Daptomycin injection comes as a powder to be added to fluid and injected into a vein by a doctor or nurse. It is usually infused (injected slowly) over a period of 30 or 60 minutes. Daptomycin can also be injected over 2 minutes in patients 18 years or older. It is usually given once a day. The length of your treatment depends on the type of infection being treated and your response to daptomycin treatment. You may receive daptomycin injection in a hospital or you may administer the medication at home. If you will be using daptomycin injection at home, your healthcare provider will show you how to infuse the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems infusing daptomycin injection.
You should begin to feel better during the first few days of treatment with daptomycin injection. If your symptoms do not improve or if they get worse, call your doctor.
Use daptomycin injection until you finish the prescription, even if you feel better. If you stop using daptomycin injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before using daptomycin injection,
Unless your doctor tells you otherwise, continue your normal diet.
Daptomycin injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
Daptomycin injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at Web Site. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to daptomycin injection.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are using daptomycin injection.
Do not let anyone else take your medication. If you still have symptoms of infection after you finish daptomycin injection, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: March 15, 2019.