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Grass Pollen Extract

Supplement Forms/Alternate Names:

6-grass pollen5-grass pollenRye grass pollen extract


Grass pollen extract refers to compounds found in the pollen made by grass. It can be taken as pill or liquid extract. Grass pollen extract has been used to ease allergy symptoms and to improve prostate health.


100 milligrams 1 to 2 times daily

What Research Shows

May Be Effective

  • Chronic prostatitis/chronic pelvic pain —may ease symptoms B1, B2

Not Enough Data to Assess

  • Benign Prostatic Hyperplasia (BPH) A1

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

Safety Notes

It is likely safe to take grass pollen extract in small doses for a short time, but rash and throat irritation may happen. Not enough studies have been done to say whether it is safe to use for a long period. It is also not known whether it is safe to take by women who are pregnant or breastfeeding.


Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.



A. Benign Prostatic Hyperplasia

A1. McNicholas T, Kirby R. Benign prostatic hyperplasia and male lower urinary tract symptoms (LUTS). BMJ Clin Evid. 2011 Aug 26;2011. pii: 1801.

B. Chronic Prostatitis/Chronic Pelvic Pain Syndrome

B1. Wagenlehner FM, Schneider H, et al. A pollen extract (Cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome: a multicenter, randomised, prospective, double-blind, placebo-controlled phase 3 study. Eur Urol. 2009;56(3):544-551.

B2. Iwamura H, Koie T, et al. Eviprostat has an identical effect compared to pollen extract (Cernilton) in patients with chronic prostatitis/chronic pelvic pain syndrome: a randomized, prospective study. BMC Urol. 2015 Dec 7;15:120.

Last reviewed February 2020 by EBSCO NAT Review Board Eric Hurwitz, DC  Last Updated: 5/27/2020