Granisetron transdermal patches are used to prevent nausea and vomiting caused by chemotherapy. Granisetron is in a class of medications called 5HT3inhibitors. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting.
Granisetron transdermal comes as a patch to apply to the skin. It is usually applied 24 to 48 hours before chemotherapy begins. The patch should be left in place for at least 24 hours after chemotherapy is finished, but should not be worn continuously for longer than a total of 7 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Apply transdermal granisetron exactly as directed. Do not apply more patches or apply the patches more often than prescribed by your doctor.
You should apply the granisetron patch to the outer area of your upper arm. Be sure that the skin in the area where you plan to apply the patch is clean, dry, and healthy. Do not apply the patch to skin that is red, dry or peeling, irritated, or oily. Also do not apply the patch to skin that you have recently shaved or treated with creams, powders, lotions, oils, or other skin products.
After you apply your granisetron patch, you should wear it all the time until you are scheduled to remove it. You may bathe or shower normally while you are wearing the patch, but you should not soak the patch in water for long periods of time. Avoid swimming, strenuous exercise, and using saunas or whirlpools while you are wearing the patch.
If your patch loosens before it is time to remove it, you may apply medical adhesive tape or surgical bandages around the edges of the patch to keep it in place. Do not cover the entire patch with bandages or tape, and do not wrap bandages or tape all the way around your arm. Call your doctor if your patch comes more than half-way off or if it becomes damaged.
To apply the patch, follow these steps:
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before using transdermal granisetron,
Unless your doctor tells you otherwise, continue your normal diet.
Call your doctor if you forget to apply your patch at least 24 hours before you are scheduled to begin your chemotherapy.
Transdermal granisetron may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or seek emergency medical treatment:
Transdermal granisetron may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( Web Site) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. Web Site
If someone applies too many granisetron patches, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include the following:
Keep all appointments with your doctor.
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: October 15, 2016.