Alvimopan is only for short term use by hospitalized patients. You will receive no more than 15 doses of alvimopan during your hospital stay. You will not be given any additional alvimopan to take after you leave the hospital.
Talk to your doctor about the risks of taking alvimopan.
Alvimopan is used to help the bowel recover more quickly after bowel surgery, so that you can eat solid foods and have regular bowel movements. Alvimopan is in a class of medications called peripherally acting mu-opioid receptor antagonists. It works by protecting the bowel from the constipation effects of opioid (narcotic) medications that are used to treat pain after surgery.
Alvimopan comes as a capsule to take by mouth. It is usually taken once shortly before bowel surgery. After the surgery, it is usually taken twice a day for up to 7 days or until hospital discharge. Your nurse will bring your medication to you when it is time for you to receive each dose.
This medication should not be prescribed for other uses; ask your doctor or pharmacist for more information.
Before taking alvimopan,
Unless your doctor tells you otherwise, continue your normal diet.
Alvimopan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Alvimopan may cause other side effects. Tell your doctor if you have any unusual problems while taking this medication.
In one study, people who took alvimopan for up to 12 months were more likely to experience heart attacks than people who did not take alvimopan. However, in another study, people who took alvimopan for up to 7 days following bowel surgery were no more likely to experience heart attacks than people who did not take alvimopan. Talk to your doctor about the risks of taking alvimopan.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at Web Site. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Ask your doctor or pharmacist if you have any questions about alvimopan.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: November 1, 2008.