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Ribose is a sugar that the body needs to make energy. It has been used to promote heart health and boost athletic performance. Ribose has also been used to ease fatigue. It can be taken as a pill or powder. It can also be injected by a healthcare provider.


7 to 10 grams daily

What Research Shows

Not Enough Data to Assess

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

Safety Notes

It is likely safe to take ribose in small doses for a short time. Not enough studies have been done to say whether it is safe to take for a long period. It is also not known whether it is safe to take by women who are pregnant or breastfeeding.


Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse, such as:

  • People with diabetes should talk to their doctors before taking ribose. It may interact with their medicines.


1. Omron H, Illien S, et al. D-Ribose improves diastolic function and quality of life in congestive heart failure patients: a prospective feasibility study. Eur J Heart Fail. 2003 Oct;5(5):615-619.

Last reviewed July 2019 by EBSCO NAT Review Board Eric Hurwitz, DC  Last Updated: 3/30/2020