Rectal hydrocortisone is used along with other medications to treat proctitis (swelling in the rectum) and ulcerative colitis (a condition which causes swelling and sores in the lining of the large intestine and rectum). It is also used to relieve itching and swelling from hemorrhoids and other rectal problems. Hydrocortisone is in a class of medications called corticosteroids. It works by activating natural substances in the skin to reduce swelling, redness, and itching.
Hydrocortisone rectal comes as a cream, an enema, suppositories, and a foam to use in the rectum. Follow the directions on your prescription or your product label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use rectal hydrocortisone exactly as directed. Do not use it more or less of it or use it more often than prescribed by your doctor.
For proctitis, hydrocortisone rectal foam usually is used one or two times a day for 2 to 3 weeks, then if necessary, every other day until your condition improves. Hydrocortisone rectal suppositories usually are used two or three times daily for 2 weeks; may require treatment for up to 6 to 8 weeks in severe cases. Proctitis symptoms may improve within 5 to 7 days.
For hemorrhoids, hydrocortisone rectal cream usually is used in adults and children 12 years and older up to 3 or 4 times daily. If you obtained hydrocortisone without a prescription (over the counter) and your condition does not improve within 7 days, stop using it and call your doctor. Do not put the cream into your rectum with your fingers.
For ulcerative colitis, hydrocortisone rectal enema usually is used every night for 21 days. Although colitis symptoms may improve within 3 to 5 days, 2 to 3 months of regular enema use may be required. Call your doctor if your colitis symptoms do not improve within 2 or 3 weeks.
Your doctor may change your dose of rectal hydrocortisone during your treatment to be sure that you are always using the lowest dose that works for you. Your doctor may also need to change your dose if you experience unusual stress on your body such as surgery, illness, or infection. Tell your doctor if your symptoms improve or get worse or if you get sick or have any changes in your health during your treatment.
Hydrocortisone rectal suppositories may stain clothing and other fabrics. Take precautions to prevent staining when you use this medication.
Before using hydrocortisone rectal foam the first time, carefully read the written instructions that come with it. Ask your doctor or pharmacist to explain any part you do not understand.
If using a hydrocortisone rectal enema, follow these steps:
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before using rectal hydrocortisone,
Your doctor may instruct you to follow a low-salt, high potassium, or high calcium diet. Your doctor may also prescribe or recommend a calcium or potassium supplement. Follow these directions carefully.
Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.
Rectal hydrocortisone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
Children who use rectal hydrocortisone may have an increased risk of side effects including slowed growth and delayed weight gain. Talk to your child's doctor about the risks of using this medication.
People who use rectal hydrocortisone for a long time may develop glaucoma or cataracts. Talk to your doctor about the risks of using rectal hydrocortisone and how often you should have your eyes examined during your treatment.
Rectal hydrocortisone may increase your risk of developing osteoporosis. Talk to your doctor about the risks of using this medication.
Rectal hydrocortisone may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it according to the package instructions. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze or refrigerate rectal hydrocortisone products.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( Web Site) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. Web Site
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at Web Site. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to rectal hydrocortisone.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are using rectal hydrocortisone.
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: March 15, 2017.