Penicillin G (Potassium, Sodium) Injection
(pen" I sil' in)
WHY is this medicine prescribed?
Penicillin G injection is used to treat and prevent certain infections caused by bacteria. Penicillin G injection is in a class of medications called penicillins. It works by killing bacteria that cause infections.
Antibiotics such as penicillin G injection will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
HOW should this medicine be used?
Penicillin G injection comes as a powder to be mixed with water and as a premixed product. Penicillin G injection is usually injected into a muscle or vein but may also be given directly into the lining of the chest cavity, into the fluid surrounding the spinal cord, or into a joint or other areas. The number of doses you receive each day and the total length of your treatment depend on your general health, the type of infection that you have, and how well you respond to the medication.
You may receive penicillin G injection in a hospital or you may administer the medication at home. If you will be receiving penicillin G injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.
You should begin to feel better during the first few days of treatment with penicillin G injection. If your symptoms do not improve or get worse, call your doctor.
Use penicillin G injection for as long as your doctor tells you that you should, even if you feel better. If you stop using penicillin G injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
If you are using penicillin G injection to treat certain infections such as syphilis (a sexually transmitted disease), Lyme disease (an infection transmitted by tick bites that may cause problems with the heart, joints, and nervous system), or relapsing fever (an infection transmitted by tick bites that causes repeated episodes of fever), you may experience a reaction beginning one or two hours after receiving your first dose of this medication and lasting for 12 to 24 hours. Tell your doctor if you experience any of the following symptoms: fever, chills, muscle aches, headache, worsening of skin sores, fast heartbeat, fast breathing, and flushing.
Are there OTHER USES for this medicine?
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What SPECIAL PRECAUTIONS should I follow?
Before receiving penicillin G injection,
What SPECIAL DIETARY instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do IF I FORGET to take a dose?
Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.
What SIDE EFFECTS can this medicine cause?
Penicillin G injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, stop using penicillin G injection and call your doctor immediately or get emergency medical treatment:
Penicillin G injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( http://www.fda.gov/Safety/MedWatch ) or by phone (1-800-332-1088).
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online athttps://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to penicillin G injection.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are receiving penicillin G injection.
If you are diabetic and test your urine for sugar, use Clinistix or TesTape (not Clinitest) to test your urine while taking this medication.
Ask your pharmacist any questions you have about penicillin G injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: February 15, 2016.
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at firstname.lastname@example.org. Our Health Library Support team will respond to your email request within 2 business days.