Brand Name(s):

Mephyton^®

Other Name(s):

Vitamin K1

WHY is this medicine prescribed?

Phytonadione (vitamin K) is used to prevent bleeding in people with blood clotting problems or too little vitamin K in the body. Phytonadione is in a class of medications called vitamins. It works by providing vitamin K that is needed for blood to clot normally in the body.

HOW should this medicine be used?

Phytonadione comes as a tablet to take by mouth. It should be taken as directed by your doctor. Your doctor may sometimes prescribe another medication (bile salts) to take with phytonadione. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not stop taking phytonadione without talking to your doctor. Take phytonadione exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Are there OTHER USES for this medicine?

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What SPECIAL PRECAUTIONS should I follow?

Before taking phytonadione,

tell your doctor and pharmacist if you are allergic to phytonadione, any other medications, or any of the ingredients in phytonadione tablets. Ask your pharmacist for a list of the ingredients.
Do not take anticoagulants ('blood thinners') such as warfarin (Coumadin) while you are taking phytonadione unless told to do so by your doctor.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antibiotics; salicylate pain relievers such as aspirin or aspirin-containing products, choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan's, others), and salsalate (Argesic, Disalcid, Salgesic). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
if you are taking orlistat (Xenical), take it 2 hours before or 2 hours after phytonadione.
tell your doctor if you have or have ever had liver disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking phytonadione, call your doctor.

What SPECIAL DIETARY instructions should I follow?

Talk to your doctor about the amount of vitamin K-rich foods to include in your diet while taking phytonadione. Do not increase or decrease your normal intake of foods such as green leafy vegetables, liver, broccoli, and cauliflower without checking with your doctor.

What should I do IF I FORGET to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Tell your doctor if you miss any doses. Do not take a double dose to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. You should always protect phytonadione from light. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach.http://www.upandaway.org

What OTHER INFORMATION should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to phytonadione.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

AHFS^® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: August 15, 2017.