(tem'' sir oh' li mus)
WHY is this medicine prescribed?
Temsirolimus is used to treat advanced renal cell carcinoma (RCC, a type of cancer that begins in the kidney). Temsirolimus is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that tells the cancer cells to multiply. This may help slow the growth of tumors.
HOW should this medicine be used?
Temsirolimus comes as a solution (liquid) to be given by infusion (slow injection into a vein) over 30 to 60 minutes. It is usually given by a doctor or nurse in a doctor's office or infusion center. Temsirolimus is usually given once every week.
You may experience symptoms such as hives, rash, itching, difficulty breathing or swallowing, swelling of the face, flushing, or chest pain. Tell your doctor or other healthcare provider if you experience these symptoms while you are receiving temsirolimus. Your doctor may prescribe other medications to help prevent or relieve these symptoms. Your doctor will probably give you these medications before you receive each dose of temsirolimus.
What SPECIAL PRECAUTIONS should I follow?
Before taking temsirolimus,
What SPECIAL DIETARY instructions should I follow?
Do not eat grapefruit or drink grapefruit juice while taking this medication.
What should I do IF I FORGET to take a dose?
If you miss an appointment to receive a dose of temsirolimus, call your doctor right away.
What SIDE EFFECTS can this medicine cause?
Temsirolimus may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
Temsirolimus may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( http://www.fda.gov/Safety/MedWatch ) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
This medication will be stored at your doctor's office or clinic.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online athttps://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include:
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to temsirolimus.
Ask your doctor if you have any questions about your treatment with temsirolimus.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Last Reviewed: September 1, 2010.
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