(Glycine Encephalopathy; Hepatic Encephalopathy; Statin Encephalopathy; Uremic Encephalopathy; Hashimoto Encephalopathy; Hypertensive Encephalopathy; Toxic-metabolic Encephalopathy)
by Cynthia M. Johnson, MA
Encephalopathy is a disease of the brain that causes problem with how it works. There are many types. A key sign is a change in mental state, such as confusion and sudden mood changes.
There are many causes. Some common ones are:
The main problem is a change in mental state, such as:
Other problems may be:
The doctor will ask you or your caregiver about your symptoms and health history. A physical exam will be done.
These tests may be done to confirm the diagnosis and find the cause:
The cause will need to be treated. This may be done with:
Many causes cannot be prevented. The risk of some causes may be lowered by:
National Institute of Diabetes and Digestive and Kidney Disorders
National Institute of Neurological Disorders and Stroke
Eencephalopathy information page. National Institute of Neurological Disorders and Stroke website. Available at: https://www.ninds.nih.gov/Disorders/All-Disorders/Encephalopathy-Information-Page. Updated March 27, 2019. Accessed April 16, 2020.
Hepatic encephalopathy. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/hepatic-encephalopathy. Updated July 23, 2019. Accessed April 16, 2020.
Wijdicks EF. Hepatic Encephalopathy. N Engl J Med. 2016 Oct 27;375(17):1660-1670.
Last reviewed February 2020 by EBSCO Medical Review Board Rimas Lukas, MD
Last Updated: 4/16/2020
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