Paclitaxel (with albumin) Injection
(pak'' li tax' el)
Paclitaxel (with albumin) injection may cause a large decrease in the number of white blood cells (a type of blood cell that is needed to fight infection) in your blood. This increases the risk that you will develop a serious infection. You should not receive paclitaxel (with albumin) if you already have a low number of white blood cells. Your doctor will order laboratory tests before and during your treatment to check the number of white blood cells in your blood. Your doctor will delay or interrupt your treatment if the number of white blood cells is too low. Call your doctor immediately if you develop a temperature greater than 100.4 °F (38 °C); a sore throat; cough; chills; difficult, frequent, or painful urination; or other signs of infection during your treatment with paclitaxel injection.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to paclitaxel (with albumin) injection.
Talk to your doctor about the risks of receiving paclitaxel (with albumin) injection.
WHY is this medicine prescribed?
Paclitaxel (with albumin) injection is used to treat breast cancer that has spread to other parts of the body and has not improved or worsened after treatment with other medications. Paclitaxel (with albumin) injection is also used in combination with other chemotherapy medications to treat non-small cell lung cancer (NSCLC). Paclitaxel (with albumin) injection is used in combination with gemcitabine (Gemzar) to treat cancer of the pancreas. Paclitaxel is in a class of medications called antimicrotubule agents. It works by stopping the growth and spread of cancer cells.
HOW should this medicine be used?
Paclitaxel (with albumin) injection comes as a powder to be mixed with liquid to be injected over 30 minutes intravenously (into a vein) by a doctor or nurse in a medical facility. When paclitaxel (with albumin) injection is used to treat breast cancer, it is usually given once every 3 weeks. When paclitaxel (with albumin) injection is used to treat non-small cell lung cancer it is usually given on days 1, 8, and 15 as part of a 3 week cycle. When paclitaxel (with albumin) injection is used to treat cancer of the pancreas, it is usually given on day 1, 8, and 15 as part of a 4 week cycle. These cycles may be repeated for as long as your doctor recommends.
Your doctor may need to interrupt your treatment, reduce your dose, or stop your treatment depending on your response to the medication and any side effects that you experience. Be sure to tell your doctor how you are feeling during your treatment.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Are there OTHER USES for this medicine?
Paclitaxel injection is also sometimes used to treat cancer of the head and neck, esophagus (tube that connects the mouth and stomach), bladder, endometrium (lining of the uterus), and cervix (opening of the uterus). Talk to your doctor about the risks of using this medication for your condition.
What SPECIAL PRECAUTIONS should I follow?
Before receiving paclitaxel (with albumin) injection,
What SPECIAL DIETARY instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What SIDE EFFECTS can this medicine cause?
Paclitaxel (with albumin) may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
Paclitaxel (with albumin) may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( http://www.fda.gov/Safety/MedWatch ) or by phone (1-800-332-1088).
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online athttps://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include:
What OTHER INFORMATION should I know?
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: January 15, 2019.
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