Osteosarcoma is a common form of bone cancer. It can spread to other parts of the body.
The cause is not known. It may be due to changes in genes.
It is more common in boys 10-19 years old.
Here are some factors that may raise your risk:
Genetic problems, such as
and Li-Fraumeni syndrome
Symptoms are usually in the upper and lower long bones and pelvis. They are:
- Bone pain that may worsen with activity
- A large lump
You will be asked about your child’s symptoms and health history. A physical exam will be done.
Pictures may be taken of your child's body. This can be done with:
of the site can confirm the diagnosis.
When cancer is found, your child will be referred to a team that focuses on cancer in children. The doctor will do staging tests to find out if the cancer has spread. Treatment depends on the stage and site of the cancer. Talk with the doctor and healthcare team about the best plan for your child.
Your child may have:
Surgery removes the tumor, nearby tissues, and nearby lymph nodes. The limb may need to be
amputated. The doctor will try to remove the cancer without amputation. Sometimes, treatment with chemotherapy can help avoid it.
is the use of drugs to kill cancer cells. The drugs enter the bloodstream and travel through the body killing mostly cancer cells.
With this therapy, radiation is aimed at the tumor to kill the cancer cells.
Radiation of Tumor
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There are no current methods to prevent osteosarcoma.
Childhood cancer: osteosarcoma. Kids Health—Nemours Foundation website. Available at: https://kidshealth.org/en/parents/cancer-osteosarcoma.html. Accessed January 29, 2021.
Osteosarcoma in children. Boston Children's Hospital website. Available at: http://www.childrenshospital.org/conditions-and-treatments/conditions/osteosarcoma. Accessed January 29, 2021.
Osteosarcoma in children. EBSCO DynaMed website. Available at: http://www.dynamed.com/topics/dmp~AN~T920563/Osteosarcoma-in-children. Accessed January 29, 2021.
Last reviewed September 2020 by
EBSCO Medical Review Board
Mohei Abouzied, MD, FACP
Last Updated: 1/29/2021