A. Acute Pancreatitis
A1. Asrani V, Chang WK, et al. Glutamine supplementation in acute pancreatitis: a meta-analysis of randomized controlled trials. Pancreatology. 2013;13(5):468-474.
A2. Jafari T, Feizi A, et al. Parenteral immunonutrition in patients with acute pancreatitis: a systematic review and meta-analysis. Clin Nutr. 2015 Feb;34(1):35-43.
A3. Yong L, Lu QP, et al. Efficacy of Glutamine-Enriched Nutrition Support for Patients With Severe Acute Pancreatitis: A Meta-Analysis. JPEN J Parenter Enteral Nutr. 2016 Jan;40(1):83-94.
A4. Castro-Gutiérrez V, Rada G. IS there a role for glutamine supplementation in the management of acute pancreatitis? Medwave. 2016;16(3):e6512.
B. Cancer Treatment Support
B1. Worthington HV, Clarkson JE, et al. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev. 2011 Apr 13;(4):CD000978.
B2. Sun J, Wang H, et al. Glutamine for chemotherapy induced diarrhea: a meta-analysis. Asia Pac J Clin Nutr. 2012;21(3):380-385.
B3. Leggett S, Koczwara B, et al. The impact of complementary and alternative medicines on cancer symptoms, treatment side effects, quality of life, and survival in women with breast cancer--a systematic review. Nutr Cancer. 2015;67(3):373-391.
B4. Papanikolopoulou A, Syrigos KN, et al. The role of glutamine supplementation in thoracic and upper aerodigestive malignancies. Nutr Cancer. 2015;67(2):231-237.
B5. Ward EJ, Henry LM, et al. Nutritional support in children and young people with cancer undergoing chemotherapy. Cochrane Database Syst Rev. 2015 Aug 24;(8):CD003298.
B6. Brami C, Bao T, et al. Natural products and complementary therapies for chemotherapy-induced peripheral neuropathy: A systematic review. Crit Rev Oncol Hematol. 2016 Feb;98:325-334.
B7. Sayles C, Hickerson SC, et al. Oral Glutamine in Preventing Treatment-Related Mucositis in Adult Patients With Cancer: A Systematic Review. Nutr Clin Pract. 2016 Apr;31(2):171-179.
B8. Leung HW, Chan AL. Glutamine in Alleviation of Radiation-Induced Severe Oral Mucositis: A Meta-Analysis. Nutr Cancer. 2016;68(5):734-742.
B9. Cao DD, Xu HL, et al. Therapeutic role of glutamine in management of radiation enteritis: a meta-analysis of 13 randomized controlled trials. Oncotarget. 2017;8(18):30595-30605.
B10. Mochamat, Cuhls H, et al. A systematic review on the role of vitamins, minerals, proteins, and other supplements for the treatment of cachexia in cancer: a European Palliative Care Research Centre cachexia project. J Cachexia Sarcopenia Muscle. 2017 Feb;8(1):25-39.
B11. Lawrie TA, Green JT, et al. Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers. Cochrane Database Syst Rev. 2018 Jan 23;1:CD012529.
C. Critical Illness
C1. Tao KM, Li XQ, et al. Glutamine supplementation for critically ill adults. Cochrane Database Syst Rev. 2014 Sep 9;(9):CD010050.
C2. Oldani M, Sandini M, et al. Glutamine Supplementation in Intensive Care Patients: A Meta-Analysis of Randomized Clinical Trials. Medicine (Baltimore). 2015 Aug;94(31):e1319.
C3. van Zanten AR, Dhaliwal R, et al. Enteral glutamine supplementation in critically ill patients: a systematic review and meta-analysis. Crit Care. 2015 Aug 18;19:294.
C4. Mottaghi A, Yeganeh MZ, et al. Efficacy of glutamine-enriched enteral feeding formulae in critically ill patients: a systematic review and meta-analysis of randomized controlled trials. Asia Pac J Clin Nutr. 2016;25(3):504-512.
C5. Stehle P, Ellger B, et al. Glutamine dipeptide-supplemented parenteral nutrition improves the clinical outcomes of critically ill patients: A systematic evaluation of randomised controlled trials. Clin Nutr ESPEN. 2017 Feb;17:75-85.
D. Crohn Disease
D1. Akobeng AK, Elawad M, et al. Glutamine for induction of remission in Chron’s disease; Cochrane Database Syst Rev. 2016;2:CD007348.
E. Gastroinestinal Tumor
E1. Kang K, Shu XL, et al. Effect of glutamine enriched nutrition support on surgical patients with gastrointestinal tumor: a meta-analysis of randomized controlled trials. Chin Med J (Engl). 2015 Jan 20;128(2):245-251.
F. Haematopoietic Stem Cell Transplantation
F1. Crowther M, Avenell A, et al. Systematic review and meta-analyses of studies of glutamine supplementation in haematopoietic stem cell transplantation. Bone Marrow Transplant. 2009 Oct;44(7):413-425.
G. Irritable Bowel Syndrome
G1. Zhou Q, Verne ML, et al. Randomised placebo-controlled trial of dietary glutamine supplements for post infectious irritable bowel syndrome. Gut. 2019;68(6):996-1002.
H. Liver Transplantation
H1. Langer G, Großmann K, et al. Nutritional interventions for liver-transplanted patients. Cochrane Database Syst Rev. 2012 Aug 15;(8):CD007605.
H2. Lei Q, Wang X, et al. Peri-operative immunonutrition in patients undergoing liver transplantation: a meta-analysis of randomized controlled trials. Asia Pac J Clin Nutr. 2015;24(4):583-90.
I. Major Burns
I1. Tan HB, Danilla S, et al. Immunotherapy as an adjuvant therapy for burns. Tan HB, Danilla S, et al. Cochrane Database Syst Rev. 2014;(12):CD007174.
J. Preterm Infants
J1. Moe-Byrne T, Brown JV, et al. Glutamine supplementation to prevent morbidity and mortality in preterm infants. Cochrane Database Syst Rev. 2016 Apr 18;4:CD001457.
K. Severe Gastrointestinal Disease in Infants
K1. Brown JV, Moe-Byrne T, et al. Glutamine supplementation for young infants with severe gastrointestinal disease. Cochrane Database Syst Rev. 2014 Dec 15;(12):CD005947.
L. Sickle Cell Disease
L1. Niihara Y, Miller ST, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med. 2018;379(3):226-235.