Herbs and Supplements
A1. Belcaro G, Cesarone MR, et al. Pycnogenol treatment of acute hemorrhoidal episodes. Phytother Res. 2010;24(3):438-444.
A2. Giannini I, Amato A, et al. Flavonoids mixture (diosmin, troxerutin, hesperidin) in the treatment of acute hemorrhoidal disease: a prospective, randomized, triple-blind, controlled trial. Tech Coloproctol. 2015;19(6):339-345.
A3. Corsale I, Carrieri P, et al. Flavonoid mixture (diosmin, troxerutin, rutin, hesperidin, quercetin) in the treatment of I-III degree hemorroidal disease: a double-blind multicenter prospective comparative study. Int J Colorectal Dis. 2018 Nov;33(11):1595-1600.
A4. Aziz Z, Huin WK, et al. Efficacy and tolerability of micronized purified flavonoid fractions (MPFF) for haemorrhoids: A systematic review and meta-analysis. Complement Ther Med. 2018 Aug;39:49-55.
A5. Mosavat SH, Ghahramani L, et al. Topical Allium ampeloprasum subsp Iranicum (Leek) extract cream in patients with symptomatic hemorrhoids: a pilot randomized and controlled clinical trial. J Evid Based Complementary Altern Med. 2015 Apr;20(2):132-136.
A6. Perera N, Liolitsa D, et al. Phlebotonics for haemorrhoids. Cochrane Database Syst Rev. 2012 Aug 15;(8):CD004322.
A7. Joksimovic N, Spasovski G, et al. Efficacy and tolerability of hyaluronic acid, tea tree oil and methyl-sulfonyl-methane in a new gel medical device for treatment of haemorrhoids in a double-blind, placebo-controlled clinical trial. Updates Surg. 2012 Sep;64(3):195-201.
A8. Man KM, Chen WC, et al. A randomized, double-blind, placebo-controlled trial of a Chinese herbal Sophora flower formula in patients with symptomatic haemorrhoids: a preliminary study. Afr J Tradit Complement Altern Med. 2012 Dec 31;10(2):343-351.
A9. Panpimanmas S, Sithipongsri S, et al. Experimental comparative study of the efficacy and side effects of Cissus quadrangularis L. (Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoids. J Med Assoc Thai. 2010 Dec;93(12):1360-1367.
A10. Gan T, Liu YD, et al. Traditional Chinese Medicine herbs for stopping bleeding from haemorrhoids. Cochrane Database Syst Rev. 2010 Oct 6;(10):CD006791.
A11. Alonso-Coello P, Zhou Q, et al. Meta-analysis of flavonoids for the treatment of haemorrhoids. Br J Surg. 2006 Aug;93(8):909-920.
A12. Alonso-Coello P, Guyatt G, et al. Laxatives for the treatment of hemorrhoids. Cochrane Database Syst Rev. 2005 Oct 19;(4):CD004649.