A. Chronic Pancreatitis
Yaghoobi M, McNabb-Baltar J, et al. Pancreatic Enzyme Supplements Are Not Effective for Relieving Abdominal Pain in Patients with Chronic Pancreatitis: Meta-Analysis and Systematic Review of Randomized Controlled Trials. Can J Gastroenterol Hepatol. 2016;2016:8541839.
B. Post-Procedure Ecchymosis or Edema
Ho D, Jagdeo J, et al. Is There a Role for Arnica and Bromelain in Prevention of Post-Procedure Ecchymosis or Edema? A Systematic Review of the Literature. Dermatol Surg. 2016 Apr;42(4):445-463.
C. Third Molar Surgery
Mendes ML, do Nascimento-Júnior EM, et al. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials. Med Oral Patol Oral Cir Bucal. 2019 Jan 1;24(1):e61-e69.
de Souza GM, Fernandes IA, et al. Is bromelain effective in controlling the inflammatory parameters of pain, edema, and trismus after lower third molar surgery? A systematic review and meta-analysis. Phytother Res. 2019 Mar;33(3):473-481.
Chandanwale A, Langade D, et al. A Randomized, Clinical Trial to Evaluate Efficacy and Tolerability of Trypsin:Chymotrypsin as Compared to Serratiopeptidase and Trypsin:Bromelain:Rutoside in Wound Management. Adv Ther. 2017;34(1):180-198.