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Health Library Home>Conditions InDepth>Article

Diagnosis of Celiac Disease

by Cynthia M. Johnson, MA
En Español (Spanish Version)
Main Page
Risk Factors
Symptoms
Diagnosis
Treatment
Screening
Reducing Your Risk
Talking to Your Doctor
Living With Celiac Disease
Resource Guide

The doctor will ask about your symptoms and health history. A physical exam will be done. This may be enough to suspect celiac disease. Tests may be done to confirm the disease or rule out other health problems, such as an infection or food allergy.

Finding the disease early can lead to early treatment. This can slow or stop damage. Tests for celiac disease are:

Blood Tests

A blood test will be done to look for gluten antibodies. This is a sign that the body is reacting to gluten. This can confirm the diagnosis.

Celiac disease often runs in families. Genetic testing may be done to rule out the disease as a cause.

Biopsy

An upper GI endoscopy uses a scope that is passed down the throat. It lets the doctor look at the inside of the intestine.

Tools can also be passed through the scope to do a biopsy. A sample of the intestine will be removed and checked in a lab. This will show any damage and help confirm the diagnosis.

Endoscopy

Copyright © Nucleus Medical Media, Inc.

REFERENCES:

Caio G, Volta U, et al. Celiac disease: a comprehensive current review. BMC Med. 2019 Jul 23;17(1):142.

Celiac disease. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/celiac-disease. Accessed January 4, 2021.

Celiac disease. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/gastrointestinal-disorders/malabsorption-syndromes/celiac-disease. Accessed January 4, 2021.

Diagnosis of celiac disease. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: https://www.niddk.nih.gov/health-information/digestive-diseases/celiac-disease/diagnosis. Accessed January 5, 2021.

What is celiac disease? Celiac Disease Foundation website. Available at: https://celiac.org/celiac-disease/understanding-celiac-disease-2/what-is-celiac-disease. Accessed January 4, 2021.

Last reviewed December 2020 by EBSCO Medical Review Board Daniel A. Ostrovsky, MD  Last Updated: 1/4/2021

EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.

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4600 38th Street
P.O. Box 1800
Columbus, Nebraska 68602-1800
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