References►
A. Allergic Rhinitis
A1. Wu S, Xiao D. Effect of curcumin on nasal symptoms and airflow in patients with perennial allergic rhinitis. Ann Allergy Asthma Immunol. 2016 Dec;117(6):697-702.e1.
B. Amyotrophic Lateral Sclerosis
B1. Ahmadi M, Agah E, et al. Safety and Efficacy of Nanocurcumin as Add-On Therapy to Riluzole in Patients With Amyotrophic Lateral Sclerosis: A Pilot Randomized Clinical Trial. Neurotherapeutics. 2018 Apr;15(2):430-438.
C. Cancer Treatment Support
C1. Ryan JL, Heckler CE, et al. Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients. Radiat Res. 2013 Jul;180(1):34-43.
C2. Palatty PL, Azmidah A, et al. Topical application of a sandal wood oil and turmeric based cream prevents radiodermatitis in head and neck cancer patients undergoing external beam radiotherapy: a pilot study. Br J Radiol. 2014 Jun;87(1038):20130490.
D. Chronic Kidney Disease
D1. Pakfetrat M, Basiri F, et al. Effects of turmeric on uremic pruritus in end stage renal disease patients: a double-blind randomized clinical trial. J Nephrol. 2014 Apr;27(2):203-207.
E. Cognitive Function
E1. Rainey-Smith SR, Brown BM, et al. Curcumin and cognition: a randomised, placebo-controlled, double-blind study of community-dwelling older adults. Br J Nutr. 2016 Jun;115(12):2106-2113.
E2. Small GW, Siddarth P, et al. Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial. Am J Geriatr Psychiatry. 2018 Mar;26(3):266-277.
F. Crohn Disease
F1. Schneider A, Hossain I, et al. Comparison of remicade to curcumin for the treatment of Crohn's disease: A systematic review. Complement Ther Med. 2017 Aug;33:32-38.
G. Depression
G1. Lopresti AL, Maes M, et al. Curcumin for the treatment of major depression: a randomised, double-blind, placebo controlled study. J Affect Disord. 2014;167:368-375.
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G3. Esmaily H, Sahebkar A, et al. An investigation of the effects of curcumin on anxiety and depression in obese individuals: A randomized controlled trial. Chin J Integr Med. 2015 May;21(5):332-338.
G4. Yu JJ, Pei LB, et al. Chronic Supplementation of Curcumin Enhances the Efficacy of Antidepressants in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. J Clin Psychopharmacol. 2015 Aug;35(4):406-410.
G5. Al-Karawi D, Al Mamoori DA, et al. The Role of Curcumin Administration in Patients with Major Depressive Disorder: Mini Meta-Analysis of Clinical Trials. Phytother Res. 2016 Feb;30(2):175-183.
G6. Lopresti AL, Drummond PD. Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo-controlled study. J Affect Disord. 2017 Jan 1;207:188-196.
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H. Diabetes
H1. Chuengsamarn S, Rattanamongkolgul S, et al. Curcumin extract for prevention of type 2 diabetes. Diabetes Care. 2012 Nov;35(11):2121-2127.
H2. Panahi Y, Khalili N, et al. Effects of Curcuminoids Plus Piperine on Glycemic, Hepatic and Inflammatory Biomarkers in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind Placebo-Controlled Trial. Drug Res (Stuttg). 2018 Jul;68(7):403-409.
I. Heart Attack
I1. Wongcharoen W, Jai-Aue S, et al. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. Am J Cardiol. 2012 Jul 1;110(1):40-44.
J. High Cholesterol
J1. Ferguson JJA, Stojanovski E, et al. Curcumin potentiates cholesterol-lowering effects of phytosterols in hypercholesterolaemic individuals. A randomised controlled trial. Metabolism. 2018 May;82:22-35.
K. Human Papillomavirus Infection
K1. Basu P, Dutta S, et al. Clearance of cervical human papillomavirus infection by topical application of curcumin and curcumin containing polyherbal cream: a phase II randomized controlled study. Asian Pac J Cancer Prev. 2013;14(10):5753-5759.
L. Impaired Glucose Tolerance
L1. Demmers A, Korthout H, et al. Effects of medicinal food plants on impaired glucose tolerance: A systematic review of randomized controlled trials. Diabetes Res Clin Pract. 2017 Sep;131:91-106.
M. Inflammatory Bowel Disease
M1. Ng SC, Lam YT, et al. Systematic review: the efficacy of herbal therapy in inflammatory bowel disease. Aliment Pharmacol Ther. 2013 Oct;38(8):854-863.
M2. Langhorst J, Wulfert H, et al. Systematic review of complementary and alternative medicine treatments in inflammatory bowel diseases. J Crohns Colitis. 2015 Jan;9(1):86-106.
N. Intestinal Adenoma
N1. Cruz-Correa M, Hylind LM, et al. Efficacy and Safety of Curcumin in Treatment of Intestinal Adenomas in Patients With Familial Adenomatous Polyposis. Gastroenterology. 2018 Sep;155(3):668-673.
O. Irritable Bowel Syndrome
O1. Portincasa P, Bonfrate L, et al. Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome. J Gastrointestin Liver Dis. 2016 Jun;25(2):151-157.
P. Metabolic Syndrome
P1. Yang YS, Su YF, et al. Lipid-lowering effects of curcumin in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled trial. Phytother Res. 2014 Dec;28(12):1770-1777.
P2. Di Pierro F, Bressan A, et al. Potential role of bioavailable curcumin in weight loss and omental adipose tissue decrease: preliminary data of a randomized, controlled trial in overweight people with metabolic syndrome. Preliminary study. Eur Rev Med Pharmacol Sci. 2015 Nov;19(21):4195-4202.
Q. Molar Removal
Q1. Maulina T, Diana H, et al. The efficacy of curcumin in managing acute inflammation pain on the post-surgical removal of impacted third molars patients: A randomised controlled trial. J Oral Rehabil. 2018 Sep;45(9):677-683.
R. Non-alcoholic Fatty Liver Disease
R1. Panahi Y, Kianpour P, et al. Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial. J Cardiovasc Pharmacol. 2016 Sep;68(3):223-229.
R2. Rahmani S, Asgary S, et al. Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial. Phytother Res. 2016 Sep;30(9):1540-1548.
R3. Hewling, S, Kalman, D. Curcumin: A review of Its Effects on Human Health. Foods. 2017;6(10):92.
R4. Panahi Y, Kianpour P, et al. Efficacy and Safety of Phytosomal Curcumin in Non-alcoholic Fatty Liver Disease: A Randomized Control Trial. Drug Res (Stuttg). 2017;67(4):244-251.
R5. Navekar R, Rafraf M, et al. Turmeric Supplementation Improves Serum Glucose Indices and Leptin Levels in Patients with Nonalcoholic Fatty Liver Diseases. J Am Coll Nutr. 2017 May-Jun;36(4):261-267.
S. Obesity
S1. Mohammadi A, Sahebkar A, et al. Effects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trial. Phytother Res. 2013 Mar;27(3):374-379.
T. Oral Leukoplakia
T1. Kuriakose MA, Ramdas K, et al. A Randomized Double-Blind Placebo-Controlled Phase IIB Trial of Curcumin in Oral Leukoplakia. Cancer Prev Res (Phila). 2016 Aug;9(8):683-691.
U. Osteoarthritis
U1. Kaptniratsaikul V, Thanakhumpyorn S, et al. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med. 2009;15(8):898-907.
U2. Belcaro G, Cesarone MR, et al. Efficacy and safety of Meriva, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Altern Med Rev. 2010;15(4):227-244.
U3. Madhu K, Chanda K, et al. Safety and efficacy of Curcuma longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trial. Inflammopharmacology. 2013 Apr;21(2):129-136.
U4. Nakagawa Y, Mukai S, et al. Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study. J Orthop Sci. 2014 Nov;19(6):933-939.
U5. Panahi Y, Rahimnia AR, et al. Curcuminoid treatment for knee osteoarthritis: a randomized double-blind placebo-controlled trial. Phytother Res. 2014 Nov;28(11):1625-1631.
U6. Daily JW, Yang M, et al. Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Med Food. 2016 Aug;19(8):717-729.
U7. Onakpoya IJ, Spencer EA, et al. Effectiveness of curcuminoids in the treatment of knee osteoarthritis: a systematic review and meta-analysis of randomized clinical trials. Int J Rheum Dis. 2017 Apr;20(4):420-433.
U8. Del Grossi Moura M, Lopes LC, et al. Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis. Phytother Res. 2017 Nov;31(11):1676-1685.
U9. Haroyan A, Mukuchyan V, et al. Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study. BMC Complement Altern Med. 2018 Jan 9;18(1):7.
U10. Liu X, Machado GC, et al. Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis. Br J Sports Med. 2018 Feb;52(3):167-175.
U11. Bannuru RR, Osani MC, et al. Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis. Semin Arthritis Rheum. 2018 Dec;48(3):416-429.
V. Painful Conditions
V1. Sahebkar A, Henrotin Y. Analgesic Efficacy and Safety of Curcuminoids in Clinical Practice: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pain Med. 2016 Jun;17(6):1192-1202.
W. Pancreatic Cancer
W1. Pastorelli D, Fabricio ASC, et al. Phytosome complex of curcumin as complementary therapy of advanced pancreatic cancer improves safety and efficacy of gemcitabine: Results of a prospective phase II trial. Pharmacol Res. 2018 Jun;132:72-79.
X. Premenstrual Syndrome
X1. Khayat S, Fanaei H, et al. Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial. Complement Ther Med. 2015 Jun;23(3):318-324.
Y. Psoriasis
Y1. Bahraini P, Rajabi M, et al. Turmeric tonic as a treatment in scalp psoriasis: A randomized placebo-control clinical trial. J Cosmet Dermatol. 2018 Jun;17(3):461-466.
Z. Rheumatoid Arthritis
Z1. Amalraj A, Varma K, et al. A Novel Highly Bioavailable Curcumin Formulation Improves Symptoms and Diagnostic Indicators in Rheumatoid Arthritis Patients: A Randomized, Double-Blind, Placebo-Controlled, Two-Dose, Three-Arm, and Parallel-Group Study. J Med Food. 2017 Oct;20(10):1022-1030.
AA. Sulfur Mustard Intoxication
AA1. Panahi Y, Ghanei M, et al. Short-term Curcuminoid Supplementation for Chronic Pulmonary Complications due to Sulfur Mustard Intoxication: Positive Results of a Randomized Double-blind Placebo-controlled Trial. Drug Res (Stuttg). 2015 Nov;65(11):567-573.
BB. Ulcerative Colitis
BB1. Hanai, H, Lida T, Takeuchi K, et al. Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind placebo-controlled trial. Clin Gastroentreol Hepatol. 2006;4(12):1502-6.
BB2. Kumar S, Ahuja V, et al. Curcumin for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev. 2012 Oct 17;10:CD008424.
BB3. Lang A, Salomon N, et al. Curcumin in Combination With Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2015 Aug;13(8):1444-9.e1.
BB4. Grammatikopoulou MG, Gkiouras K, et al. Oral Adjuvant Curcumin Therapy for Attaining Clinical Remission in Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2018 Nov 12;10(11). pii: E1737.
