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Gamma Oryzanol

Introduction

Gamma oryzanol is a compound that comes from rice bran oil. It has been used to boost athletic and cognitive performance. It can be taken as a pill. It can also be taken by eating or cooking with rice bran oil.

50 milligrams 3 to 4 times daily

What Research Shows

May Be Effective

• Dementia—may improve symptoms of agitation and irritability when used with standard treatment^A1 

Not Enough Data to Assess

• High blood pressure^B1 
• High cholesterol^C1 
• Muscle strength^D1 

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

Safety Notes

It is likely safe to take gamma oryzanol for a short time. Not enough studies have been done to say whether it is safe to take for a long period.

Interactions

Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.

References [ + ]

A. Dementia

A1. Fuji M, Butler JP, et al. Gamma-oryzanol for behavioural and psychological symptoms of dementia. Psychogeriatrics. 2018;18(2):151-152.

B. High blood pressure

B1. Devarajan S, Singh R, et al. A blend of sesame oil and rice bran oil lowers blood pressure and improves the lipid profile in mild-to-moderate hypertensive patients. J Clin Lipidol. 2016 Mar-Apr;10(2):339-349.

C. High Cholesterol

C1. Devarajan S, Singh R, et al. A blend of sesame oil and rice bran oil lowers blood pressure and improves the lipid profile in mild-to-moderate hypertensive patients. J Clin Lipidol. 2016 Mar-Apr;10(2):339-349.

D. Muscle Strength

D1. Eslami S, Esa NM, et al. Effects of gamma oryzanol supplementation on anthropometric measurements & muscular strength in healthy males following chronic resistance training. Indian J Med Res. 2014;139(6):857-863.

Last reviewed July 2019 by EBSCO NAT Review Board Eric Hurwitz, DC
Last Updated: 5/6/2020

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