Print | Search | Send-to-Friend | Health Library Home

Chronic Fatigue Syndrome

(CFS; Systemic Exertion Intolerance Disease; SEID; Myalgic Encephalomyelitis/Chronic Fatigue Syndrome; ME/CFS )

by Amy Scholten, MPH

• Definition • Causes • Risk Factors • Symptoms • Diagnosis • Treatment • Prevention
En Español (Spanish Version)
More InDepth Information on This Condition
 

Definition

Chronic fatigue syndrome (CFS) is a condition that causes long-term, extreme tiredness. The tiredness is not relieved by bed rest. This can lead to problems doing daily activities.

 

Causes    TOP

The cause of CFS is not known. It may be linked to an infection or problems with the immune, endocrine, or nervous system.

 

Risk Factors    TOP

CFS is more common in women than men. It tends to be seen in adults ages 30 to 40 years old. However, CFS can happen at any age. Other things that raise the risk are:

  • Recent infection from a virus, fungus, or bacteria
  • Exposure to a toxin
  • Recent vaccination
  • Trauma—physical or emotional
  • Family history of CFS
  • An immune system problem
  • Long term stress
  • Allergies or sensitivities to foods, chemicals, odors, medicines, light, or noise
 

Symptoms    TOP

Symptoms vary from person to person. They may be:

  • New and lasting tiredness that:
    • Is not relieved with bed rest
    • Often gets worse with physical or mental activity
    • Cannot be explained by another health condition
  • Unexplained pain for more than 6 months, such as:
    • Muscle aches and headaches
    • Joint pain
    • Sore throat
    • Tender lymph nodes
  • Confusion, memory problems, and not being able to focus
  • Irritability, anxiety, panic attacks, mood swings, or depression
  • Problems sleeping
  • Vision problems
  • Lightheadedness, balance problems, or fainting
  • Chills and night sweats
 

Diagnosis    TOP

The doctor will ask about your symptoms and health history. A physical exam may be done. There are no specific tests to diagnose CFS.

To diagnose CFS, the doctor must rule out other health conditions first. This may take a long time.

 

Treatment    TOP

There is no cure for CFS. The goal is to manage symptoms and improve wellbeing. Treatment options are:

  • Moderate physical activity—monitored by a doctor or physical therapist
  • Therapies such as:
    • Massage
    • Stretching
    • Tai chi
    • Yoga
  • A well-balanced diet
  • Counseling, cognitive-behavioral therapy, and stress management techniques
  • Medicines, such as:
    • Antidepressants and anti-anxiety medicines
    • Pain medicines, such as ibuprofen and acetaminophen
    • Stimulants—to help mental function
    • Sedatives—to help with insomnia
 

Prevention    TOP

There are no current guidelines to prevent CFS.

RESOURCES:

Centers for Disease Control and Prevention
https://www.cdc.gov

Solve ME/CFS Initiative
http://solvecfs.org

CANADIAN RESOURCES:

Health Canada
https://www.canada.ca

The College of Family Physicians of Canada
http://www.cfpc.ca

REFERENCES:

Bested A. Myalgic encephalomyelitis/chronic fatigue syndrome: insights & advances in care. Altern Ther Health Med. 2018;24(S1):32-33.

Chronic fatigue syndrome. Family Doctor—American Academy of Family Physicians website. Available at: https://familydoctor.org/condition/chronic-fatigue-syndrome. Accessed February 26, 2021.

Myalgic encephalomyelitis/chronic fatigue syndrome. Centers for Disease Control and Prevention website. Available at: https://www.cdc.gov/me-cfs. Accessed February 26, 2021.

Chronic fatigue syndrome. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/chronic-fatigue-syndrome Accessed February 26, 2021.



Last reviewed January 2021 by EBSCO Medical Review Board Marcin Chwistek, MD
Last Updated: 2/26/2021

EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.

To send comments or feedback to our Editorial Team regarding the content please email us at healthlibrarysupport@ebsco.com. Our Health Library Support team will respond to your email request within 2 business days.

Copyright ©  EBSCO Information Services
All rights reserved.
Privacy Policy | Editorial Policy