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Feverfew is a flowering plant that grows in Central and South America. It has been used to ease pain caused by headache and migraine. It can be taken as a pill, powder, or extract.
150 milligrams once daily or 1 to 2 drops during onset of migraine
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
It is likely safe for most adults to take feverfew for a short time. Not enough studies have been done to say whether it is safe to take for a long period or while pregnant or breastfeeding.
Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse, such as:
A1. Ferro EC, Biagini AP, et al. The combined effect of acupuncture and Tanacetum parthenium on quality of life in women with headache: randomised study. Acupunct Med. 2012 Dec;30(4):252-257.
B1. Saranitzky E, White CM, Baker EL, Baker WL, Coleman CI. Feverfew for migraine prophylaxis: a systematic review. J Diet Suppl. 2009;6(2):91-103.
B2. Cady RK, Goldstein J, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic™ M) in the treatment of migraine. Headache. 2011 Jul-Aug;51(7):1078-1086.
B3. Holland S, Silberstein SD, et al; Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology. 2012 Apr 24;78(17):1346-1353.
B4. Wider B, Pittler M, et al. Feverfew for preventing migraine. Cochrane Database of Systematic Reviews. 2015:CD002286.
C1. Milić N, Milosević N, et a;. Warfarin interactions with medicinal herbs. Nat Prod Commun. 2014 Aug;9(8):1211-1216.
Last reviewed July 2019 by EBSCO NAT Review Board Eric Hurwitz, DC Last Updated: 5/6/2020