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Migraine is a type of headache that people can have several times a week or once every couple of years. Sensations called auras may come before a migraine happens. Migraines can be so strong that they make it hard to work and do normal things.
Migraines may be prevented with changes to lifestyle habits, such as avoiding triggers. Medicine and therapy are also used to prevent and treat. Some people may need surgery when these treatments are not helpful. Some people turn to natural therapies to further ease migraine symptoms and frequency.
These therapies are likely to ease symptoms:
These therapies may ease symptoms:
Magnesium, Vitamin B2, and coenzyme Q10 may ease migraine symptoms when taken together as a supplement.A2
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse. For example, vitamin B6 may interact with anti-nausea medicine taken by pregnant women. It may also interact with medicine for cancer, anxiety, and narcolepsy.
Herbs and Supplements
A1. Wider B, Pittler M, et al. Feverfew for preventing migraine. Cochrane Database of Systematic Reviews. 2015:CD002286.
A2. Gaul C, Diener HC, et al. Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial. J Headache Pain. 2015;16:516.
A3. Chiu HY, Yeh TH, et al. Effects of Intravenous and Oral Magnesium on Reducing Migraine: A Meta-analysis of Randomized Controlled Trials. Pain Physician. 2016;(1):E97-E112.
A4. Askari G, Nasiri M, et al. The effects of folic acid and pyridoxine supplementation on characteristics of migraine attacks in migraine patients with aura: A double-blind, randomized, placebo-controlled, clinical trial. Nutrition. 2017;38:74-79.
A5. Zargaran A, Borhani-Haghigi A, et al. Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura: a randomized, double-blind, placebo-controlled, crossover study. Neurol Sci. 2018;39(8):1345-1353.
A6. Long R, Zhu Y, et al. Therapeutic role of melatonin in migraine prophylaxis: A systematic review. Medicine (Baltimore). 2019;98(3):e14099.
A7. de Sousa CNS, da Silva Leite CMG, et al. Alpha-lipoic acid in the treatment of psychiatric and neurological disorders: a systematic review. Metab Brain Dis. 2019 Feb;34(1):39-52.
A8. Zeng Z, Li Y, et al. Efficacy of CoQ10 as supplementation for migraine: A meta-analysis. Acta Neurol Scand. 2019 Mar;139(3):284-293.
A9. Maghsoumi-Norouzabad L, Mansoori A, et al. Effects of omega-3 fatty acids on the frequency, severity, and duration of migraine attacks: A systematic review and meta-analysis of randomized controlled trials. Nutr Neurosci. 2018 Nov;21(9):614-623.
A10. Xiao Y, Yuan L, et al. Traditional Chinese patent medicine for prophylactic treatment of migraine: a meta-analysis of randomized, double-blind, placebo-controlled trials. Eur J Neurol. 2015 Feb;22(2):361-368.
A11. Zhou L, Chen P, et al. Systematic review and meta-analysis of traditional Chinese medicine in the treatment of migraines. Am J Chin Med. 2013;41(5):1011-1025.
B1. Xu J, Zhang FQ, et al. Acupuncture for migraine without aura: a systematic review and meta-analysis. J Integr Med. 2018 Sep;16(5):312-321.
B2. Linde K, Allais G, et al. Acupuncture for the prevention of episodic migraine. Cochrane Database Syst Rev. 2016 Jun 28;(6):CD001218.
B3. Yang Y, Que Q, et al. Verum versus sham manual acupuncture for migraine: a systematic review of randomised controlled trials. Acupunct Med. 2016 Apr;34(2):76-83.
C1. Probyn K, Bowers H, et al. Non-pharmacological self-management for people living with migraine or tension-type headache: a systematic review including analysis of intervention components. BMJ Open. 2017 Aug 11;7(8):e016670.
C2. Barnes NP. Migraine headache in children. BMJ Clin Evid. 2011 Apr 11;2011. pii: 0318.
C3. Chaibi A, Tuchin PJ, et al. Manual therapies for migraine: a systematic review. J Headache Pain. 2011 Apr;12(2):127-133.
Last reviewed November 2019 by EBSCO NAT Review Board Eric Hurwitz, DC Last Updated: 6/9/2020