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The urethra is the tube that carries urine out of the body from the bladder. Urethral syndrome is a set of symptoms of the urethra. It includes inflammation or irritation not related to an infection.
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The cause of urethral syndrome can be hard to find. Possible causes include irritation of the urethra from:
Urethral syndrome is most common in women. Factors that may lead to an undetected infection include:
Urethral syndrome may cause:
In men, urethral syndrome may specifically cause:
The doctor will ask about symptoms and past health. A physical and pelvic exam will be done. Urethral syndrome is usually diagnosed if there are no signs of an infection. Tests to rule out infections or other causes may include:
The first step may be to find what is causing the irritation. The doctor may recommend stopping use of certain products such as soaps or gels. Symptoms will often pass on their own once the irritation is removed.
Medicine may help to ease symptoms. Choices may include:
To reduce your chance of urethral syndrome, avoid the use of:
Other steps that may help include:
Centers for Disease Control and Prevention
National Institute of Diabetes and Digestive and Kidney Diseases
The Kidney Foundation of Canada
Costantine E, Zucchi A, et al. Treatment of urethral syndrome: a prospective randomized study with Nd: YAG laser. Urol Int. 2006;76:134-138.
Nongonococcal urethritis. EBSCO DynaMed website. Available at:https://www.dynamed.com/condition/nongonococcal-urethritis. Accessed September 4, 2020.
Workowski KA, Bolan GA; Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep. 2015 Jun 5;64(RR-03):1-137.
Last reviewed September 2020 by EBSCO Medical Review Board Adrienne Carmack, MD Last Updated: 01/05/2021