Chronic kidney disease (CKD) doesn’t cause problems in early stages. As it progresses, it can cause a number of symptoms. These may include:

  • Feeling weak or tired
  • Trouble sleeping— insomnia
  • Swelling of feet and ankles—edema
  • Lack of hunger
  • Increase in urine output, especially at night
  • Muscle cramping at night
  • Nausea
  • Itching
  • Breathing problems
  • Taste of metal in your mouth
  • Chest pain
  • Confusion
  • Hiccups
  • Irritability
  • Problems concentrating
  • Lower sex drive
  • Menstrual problems
  • Numbness and tingling in hands and feet— peripheral neuropathy

About chronic kidney disease. National Kidney Foundation website. Available at: Updated February 15, 2017. Accessed June 19, 2018.

Chronic kidney disease. Merck Manual Professional Version website. Available at: Updated March 2017. Accessed June 19, 2018.

Chronic kidney disease (CKD). Family Doctor—American Academy of Family Physicians website. Available at: Updated August 9, 2017. Accessed June 19, 2018.

Chronic kidney disease (CKD) in adults. EBSCO DynaMed Plus website. Available at: Updated May 14, 2018. Accessed June 19, 2018.

What is chronic kidney disease? National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: Updated June 2017. Accessed June 19, 2018.

Last reviewed May 2018 by EBSCO Medical Review Board Adrienne Carmack, MD  Last Updated: 06/19/2018