How to Say It: Polly-my-oh-sigh-tis
Polymyositis is a rare disease of the muscles. They become inflamed or swollen. This can lead to severe movement problems.
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This problem may be caused by changes in genes. The changes may cause the immune system to attack muscles.
Polymyositis is more common in women and people who are 30 to 50 years of age.
The risk of this problem is higher in people who have family members with lupus.
The muscles near the trunk of the body are most affected. Problems may be:
Polymyositis can lead to:
The doctor will ask about your symptoms and health history. A physical exam will be done.
These tests may be done to confirm muscle disease:
The disease starts slowly and gets worse over time. There is no cure. The muscles will get weaker and more painful without treatment.
The goal of treatment is to manage symptoms. Choices are:
Some options are:
Muscle weakness can cause a loss of function. Therapy may help. Options are:
There are no guidelines to prevent this health problem.
American Autoimmune Related Diseases Association
The Myositis Association
The Arthritis Society
Diagnosis. The Myositis Association website. Available at: http://www.myositis.org/learn-about-myositis/diagnosis. Accessed January 25, 2021.
Idiopathic inflammatory myopathy. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/idiopathic-inflammatory-myopathy. Accessed January 25, 2021.
Milone M. Diagnosis and Management of Immune-Mediated Myopathies. Mayo Clin Proc. 2017 May;92(5):826-837.
Myositis. Ortho Info—American Academy of Orthopaedic Surgeons website. Available at: http://orthoinfo.aaos.org/topic.cfm?topic=A00198. Accessed January 25, 2021.
Polymyositis information page. National Institute of Neurological Disorders and Stroke website. Available at: https://www.ninds.nih.gov/Disorders/All-Disorders/Polymyositis-Information-Page. Accessed January 25, 2021.
Treatment and disease management. Myositis Association website. Available at: http://www.myositis.org/learn-about-myositis/treatment. Accessed January 25, 2021.
Types of myositis. Myositis Association website. Available at: http://www.myositis.org/learn-about-myositis/types-of-myositis. Accessed January 25, 2021.
Last reviewed December 2020 by EBSCO Medical Review Board Rimas Lukas, MD Last Updated: 1/25/2021