The combination of erythromycin and benzoyl peroxide is used to treat acne. Erythromycin and benzoyl peroxide are in a class of medications called topical antibiotics. The combination of erythromycin and benzoyl peroxide works by killing the bacteria that cause acne.
The combination of erythromycin and benzoyl peroxide comes as a gel to apply to the skin. It is usually applied twice a day, in the morning and evening. To help you remember to use erythromycin and benzoyl peroxide gel, apply it at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use erythromycin and benzoyl peroxide gel exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
It may take several weeks or longer before you feel the full benefit of this medication. Continue to use this medication even if you do not see much improvement at first.
To use the gel, follow these steps:
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before using erythromycin and benzoyl peroxide,
Unless your doctor tells you otherwise, continue your normal diet.
Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Erythromycin and benzoyl peroxide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Erythromycin and benzoyl peroxide may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store Benzamycin Gel in the refrigerator but do not freeze it. If you forget to refrigerate the gel for 1 day, you may refrigerate it when you remember and continue to use it. Store Benzamycin Pak at room temperature and away from excess heat and moisture (not in the bathroom). Dispose of any unused Benzamycin Gel after 3 months.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( Web Site) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. Web Site
Keep all appointments with your doctor.
Avoid getting erythromycin and benzoyl peroxide gel on your hair or clothing. Erythromycin and benzoyl peroxide may bleach hair or colored fabric.
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: March 15, 2016.