Definition

Metabolic syndrome is a mix of things that increase your risk of heart disease, diabetes, and stroke. There are at least 3 of these:

• High blood pressure
• High triglyceride levels
• Large waistline
• Low HDL (good) cholesterol
• High fasting blood glucose

Causes

The cause of metabolic syndrome is not clear. Genes, diet, and activity level may all play a role.

Risk Factors

Metabolic syndrome is more common in people with:

• Health issues linked to metabolic problems such as:
  • Diabetes
  • High blood pressure
  • Cholesterol problems
  • Heart disease
  • Polycystic ovary syndrome
• History of gestational diabetes
• Above health issues in family members
• Low levels of physical activity
• Poor diet
• Unhealthy habits, such as smoking
• Certain medicine, such as some antipsychotics

Symptoms

There are no symptoms for metabolic syndrome itself. Too much weight in the belly is one risk factor.

Diagnosis

Many of these tests are done as part of routine check ups. Metabolic syndrome is test results show 3 or more of these:

• Fasting glucose level—100 mg/dL* (5.55 mmol/L) or higher
• Triglyceride level—150 mg/dL (1.7 mmol/L) or higher
• HDL cholesterol—40 mg/dL (1.0 mmol/L) or less in men and less than 50 mg/dL (1.3 mmol/L) in women
• Blood pressure—130/85 millimeters of mercury (mm Hg) or higher
• Waist that is 40 inches or more in men or 35 inches or more in women

*mg/dL = milligrams per deciliter of blood, mmol/L = millimoles per liter of blood

Treatment

The goal of treatment is to cut the risk of heart disease and diabetes. Steps may treat issues that caused metabolic syndrome or other heart disease risk factors. Lifestyle changes may play a large role. Medicine may be needed if lifestyle changes are not enough to lower risk.

Prevention

To decrease the risk of developing metabolic syndrome:

• Eat a balanced diet.
• Reach and keep a healthy weight.
• Aim for at least 30 minutes of exercise most days of the week.