Esomeprazole injection is used to treat gastroesophageal reflux disease (GERD; a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus [the tube between the throat and stomach]) in adults and children 1 month of age or older who have had damage to their esophagus and are unable to take esomeprazole by mouth. Esomeprazole injection is also used in adults to reduce the risk of further ulcer bleeding after an endoscopy (examination of the inside of the esophagus, stomach, and intestines). Esomeprazole is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.
Esomeprazole injection comes as a powder to be mixed with liquid and given intravenously (into a vein) by a doctor or nurse in a medical facility. For the treatment of GERD, esomeprazole is usually given intravenously once a day. For the prevention of re-bleeding after an endoscopy, esomeprazole injection is usually given as a continuous intravenous infusion for 72 hours.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before receiving esomeprazole injection,
Unless your doctor tells you otherwise, continue your normal diet.
Esomeprazole injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately, or get emergency medical help:
People who receive proton pump inhibitors such as esomeprazole may be more likely to fracture their wrists, hips, or spine than people who do not take or receive one of these medications. People who recieve proton pump inhibitors may also develop fundic gland polyps (a type of growth on the stomach lining). These risks are highest in people who take high doses of one of these medications or take them for one year or longer. Talk to your doctor about the risks of receiving esomeprazole injection.
Esomeprazole injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
Keep all appointments with your doctor and the laboratory. Your doctor may order certain laboratory tests before and during your treatment, especially if you have severe diarrhea.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are receiving esomeprazole injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: June 15, 2019.