Neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination is used to treat and prevent eye infections caused by certain bacteria and to reduce the irritation, redness, burning, and swelling of eye inflammation caused by infection, chemicals, heat, radiation, foreign bodies in the eye, and other eye conditions. Neomycin, polymyxin, and bacitracin are in a class of medications called antibiotics. They work by stopping the growth of bacteria. Hydrocortisone is in a class of medications called corticosteroids. It works by activating natural substances in the eye to reduce swelling, redness, and itching.
These ophthalmic combinations come as an ointment (containing neomycin, polymyxin, bacitracin, and hydrocortisone) to apply to the eye and as a suspension (liquid with undissolved particles) (containing neomycin, polymyxin, and hydrocortisone) to instill in the eye. It is usually used in the affected eye(s) every three to four hours depending on the condition that you have. Use neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
Do not share your medication, even with someone who was also prescribed this medication. If more than one person uses the same tube or bottle, infection may spread.
Your symptoms should begin to improve during the first few days of treatment with neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination. If symptoms of pain and swelling do not improve or get worse within 48 hours after starting treatment, stop using the medication and call your doctor.
Use neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination for as long as directed by your doctor, even if you feel better. If you stop using neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
To apply the eye ointment, follow these steps:
To instill the eye drops, follow these steps:
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before using neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination,
Unless your doctor tells you otherwise, continue your normal diet.
Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use extra ointment or suspension to make up for a missed dose.
Neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, stop using neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination and call your doctor immediately or get emergency medical treatment:
Neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. Web Site
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( Web Site) for more information if you do not have access to a take-back program.
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at Web Site. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor. If you will be using this medication for more than 10 days, your doctor will probably order certain tests to check your body's response to neomycin, polymyxin, bacitracin, and hydrocortisone ophthalmic combination.
Do not let anyone else take your medication.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: June 15, 2018.