Etelcalcetide injection is used to treat secondary hyperparathyroidism (condition in which the body produces too much parathyroid hormone [PTH; natural substance needed to control the amount of calcium in the blood]) in adults with chronic kidney disease (condition in which the kidneys stop working slowly and gradually) who are being treated with dialysis (medical treatment to clean the blood when the kidneys are not working properly.) Etelcalcetide injection is in a class of medications called calcimimetics. It works by signaling the body to produce less parathyroid hormone in order to decrease the amount of calcium in the blood.
Etelcalcetide injection comes as a solution (liquid) to inject intravenously (into a vein). It is usually given 3 times a week at the end of each dialysis session by a doctor or nurse at the dialysis center.
Your doctor will probably start you on an average dose of etelcalcetide injection and gradually adjust your dose depending on your body's response to the medication, not more than once every 4 weeks.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before receiving etelcalcetide injection,
Unless your doctor tells you otherwise, continue your normal diet.
This medication is only given with your dialysis treatment. If you miss a scheduled dialysis treatment, skip the missed dose of medication and continue your regular dosing schedule at the next dialysis session.
Etelcalcetide injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
Etelcalcetide injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at Web Site. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before and during your treatment to check your body's response to etelcalcetide injection.
Ask your pharmacist any questions you have about etelcalcetide injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: September 15, 2017.