by Cynthia M. Johnson, MA
Psychosis is the loss of contact with reality. It may result in false beliefs called delusions or sensing things that are not really there (hallucinations).
Psychosis may be caused by changes in chemicals and/or structures of the brain. Some conditions associated with psychosis include:
Risk Factors TOP
Factors that may increase your chance of psychosis include:
Symptoms can vary but may include:
You will be asked about your symptoms and medical history. A physical exam will be done. Information about alcohol use, illegal drugs, prescription medications, supplements, and herbs will also be collected. A psychiatric evaluation will be done.
Bodily fluids may be tested to look for the presence of substances that can cause problems or to look for imbalance in the body. This can be done with:
Treatment will depend on the cause of your psychosis. Talk with your doctor about the best treatment plan for you. Hospitalization may be needed until the psychosis is managed. Options may include one or more of the following:
Psychological therapy treatments are often recommended in addition to medication. There are several different types of therapies such as:
The medical team will help determine which therapy or therapies may be best.
Medications may be recommended to control symptoms. The exact type or combination will depend on symptoms and causes. Some options include:
Prevention depends on the cause of psychosis. Those at risk for psychosis may be able to prevent a psychotic episode with careful management of related condition.
National Institute of Mental Health
National Mental Health Association
Canadian Mental Health Association
Canadian Psychiatric Association
Olin SC, Mednick SA. Risk factors of psychosis: identifying vulnerable populations premorbidly. Schizophr Bull. 1996;22(2):223-240.
Psychosis. Centre for Addiction and Mental Health website. Available at:
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Accessed October 4, 2017.
Psychosis. NHS Choices website. Available at:
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Updated December 23, 2016. Accessed October 4, 2017.
Psychosis. Rethink Mental Illness website. Available at: https://www.rethink.org/diagnosis-treatment/conditions/psychosis. Updated February 2016. Accessed October 4, 2017.
What is early and first-episode psychosis? National Alliance on Mental Illness website. Available at: https://www.nami.org/getattachment/Learn-More/Mental-Health-Conditions/Early-Psychosis-and-Psychosis/NAMI-Early-Psychosis.pdf. Accessed October 4, 2017.
Last reviewed September 2018 by EBSCO Medical Review Board Adrian Preda, MD
Last Updated: 10/13/2015
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